C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenoceptor beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369295 ADRB1-001 ENSG00000043591 9606 + 10:114044056-114046908 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369295 3.642±0.00 0.413±0.00 0.065±0.00 3.883±1.61 4.067±3.95 0.535±0.30 7.124±3.77 0.730±0.00 0.191±0.14 5.078±0.70 0.083±0.00 0.669±0.79 41.078±17.44 0.406±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001R7 CIL_0001R7_0002 CGP 10:113854661-114046908
CIL_0006OP CIL_0006OP_0001 CGP 10:114044056-114174220

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001996 IEA positive regulation of heart rate by epinephrine-norepinephrine
GO:0001997 IEA positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0002024 IEA diet induced thermogenesis
GO:0002025 IEA vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0003061 IEA positive regulation of the force of heart contraction by norepinephrine
GO:0003084 IEA positive regulation of systemic arterial blood pressure
GO:0004930 IEA G-protein coupled receptor activity
GO:0004939 TAS beta-adrenergic receptor activity
GO:0004940 IEA beta1-adrenergic receptor activity
GO:0005057 IDA receptor signaling protein activity
GO:0005088 IDA Ras guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005769 IDA early endosome
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005980 IEA glycogen catabolic process
GO:0006915 IEA apoptotic process
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007266 IEA Rho protein signal transduction
GO:0007568 IEA aging
GO:0007613 IEA memory
GO:0008144 IEA drug binding
GO:0009409 IEA response to cold
GO:0010460 IEA positive regulation of heart rate
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030165 IPI PDZ domain binding
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031649 IEA heat generation
GO:0031694 IPI alpha-2A adrenergic receptor binding
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0033365 IEA protein localization to organelle
GO:0035240 IEA dopamine binding
GO:0035811 IEA negative regulation of urine volume
GO:0040015 IEA negative regulation of multicellular organism growth
GO:0042060 IEA wound healing
GO:0042596 IEA fear response
GO:0043065 IEA positive regulation of apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0045986 IEA negative regulation of smooth muscle contraction
GO:0046878 IEA positive regulation of saliva secretion
GO:0046982 IPI protein heterodimerization activity
GO:0050873 IEA brown fat cell differentiation
GO:0051379 IEA epinephrine binding
GO:0051380 IEA norepinephrine binding
GO:0051924 IEA regulation of calcium ion transport
GO:0055088 IEA lipid homeostasis
GO:0060080 IEA regulation of inhibitory postsynaptic membrane potential
GO:0061051 IEA positive regulation of cell growth involved in cardiac muscle cell development
GO:0071880 IDA adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:1900135 IEA positive regulation of renin secretion into blood stream
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038949 Adrb1-201 protein_coding Mus_musculus 0 1703
ENSMUST00000121838 Adrb3-003 protein_coding Mus_musculus 4e-21 108
ENSMUST00000117565 Adrb3-002 protein_coding Mus_musculus 4e-21 108
ENSMUST00000081438 Adrb3-001 protein_coding Mus_musculus 4e-21 108

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