C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120259 Map3k5-002 ENSMUSG00000071369 10090 + 10:19934526-20141670 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000120259
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000120259 1.044±0.20 0.939±0.23 1.155±1.44 1.018±0.28 0.754±0.00 1.487±0.37 1.150±0.21 0.501±0.01 1.302±0.24 2.352±0.94 0.605±0.00 0.189±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0008631 IDA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0010941 IGI regulation of cell death
GO:0097300 IMP programmed necrotic cell death
GO:1902170 IMP cellular response to reactive nitrogen species

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000152495 map3k5-001 protein_coding Danio_rerio 0 1155
ENSDART00000046641 map3k5-201 protein_coding Danio_rerio 0 1083
ENST00000359015 MAP3K5-001 protein_coding Homo_sapiens 0 4455
ENST00000463140 MAP3K5-002 processed_transcript Homo_sapiens 0 324

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