C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mixed lineage kinase domain-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120432 Mlkl-002 ENSMUSG00000012519 10090 - 8:111311800-111338177 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000120432
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000120432 1.878±0.19 3.302±0.52 3.095±0.25 0.087±0.02 1.368±0.28 2.977±0.92 0.599±0.26 0.444±0.13 1.076±0.36 1.426±0.30 0.270±0.12 1.520±1.44 0.992±0.62 2.813±2.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PQ CIL_0002PQ_0002 CGP 8:111270944-111338177
CIL_000168 CIL_000168_0002 CGP 8:111311797-111393824

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0019901 IPI protein kinase binding
GO:0032403 IEA protein complex binding
GO:0070207 ISS protein homotrimerization
GO:0070266 IMP necroptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000308807 MLKL-001 protein_coding Homo_sapiens 0 586
ENST00000571303 MLKL-007 nonsense_mediated_decay Homo_sapiens 0 355

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