C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mixed lineage kinase domain-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000308807 MLKL-001 ENSG00000168404 9606 - 16:74671861-74700914 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000308807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000308807 1.026±0.00 2.092±0.00 0.233±0.00 0.057±0.00 2.311±0.33 1.794±1.36 0.433±0.23 1.201±1.09 0.552±0.19 2.035±0.48 2.746±1.78 2.625±0.49 0.533±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PQ CIL_0002PQ_0001 CGP 16:74621394-74700960
CIL_000168 CIL_000168_0001 CGP 16:74671855-74774831

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IEA protein kinase binding
GO:0032403 IDA protein complex binding
GO:0070207 IDA protein homotrimerization
GO:0070266 IMP necroptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120432 Mlkl-002 protein_coding Mus_musculus 0 586
ENSMUST00000056157 Mlkl-001 protein_coding Mus_musculus 0 580

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