C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 4D, cAMP specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120664 Pde4d-011 ENSMUSG00000021699 10090 + 13:109903106-109953461 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonKidneyLiverLungMuscleOvaryTestisENSMUST00000120664
Transcript ID Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000120664 0.883±0.66 6.525±4.53 1.665±0.06 1.129±0.08 1.494±0.00 0.247±0.09 1.001±0.00 4.344±0.00 0.668±0.23 0.349±0.15

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0004114 IDA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006198 IEA cAMP catabolic process
GO:0006939 IMP smooth muscle contraction
GO:0007165 IEA signal transduction
GO:0007568 IMP aging
GO:0010880 IMP regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0030593 IMP neutrophil chemotaxis
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0034704 IDA calcium channel complex
GO:0035264 IMP multicellular organism growth
GO:0044325 IPI ion channel binding
GO:0045822 IMP negative regulation of heart contraction
GO:0046872 IEA metal ion binding
GO:0050900 IMP leukocyte migration
GO:0051117 IPI ATPase binding
GO:0060314 IMP regulation of ryanodine-sensitive calcium-release channel activity
GO:0061028 ISS establishment of endothelial barrier
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0071872 IMP cellular response to epinephrine stimulus
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:1901844 IC regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1901898 IMP negative regulation of relaxation of cardiac muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000002096 pde4ca-201 protein_coding Danio_rerio 0 719
ENSDART00000141030 pde4ca-001 protein_coding Danio_rerio 0 719
ENST00000309641 PDE4D-013 nonsense_mediated_decay Homo_sapiens 0 1790
ENST00000317118 PDE4D-020 protein_coding Homo_sapiens 0 2250
ENST00000340635 PDE4D-001 protein_coding Homo_sapiens 0 2470
ENST00000358923 PDE4D-019 protein_coding Homo_sapiens 0 2466
ENST00000360047 PDE4D-014 protein_coding Homo_sapiens 0 2470
ENST00000405755 PDE4D-015 protein_coding Homo_sapiens 0 2098
ENST00000502484 PDE4D-003 protein_coding Homo_sapiens 0 2073
ENST00000503258 PDE4D-016 protein_coding Homo_sapiens 0 2102
ENST00000505453 PDE4D-017 protein_coding Homo_sapiens 0 1792
ENST00000507116 PDE4D-012 protein_coding Homo_sapiens 0 2470
ENST00000515011 PDE4D-018 retained_intron Homo_sapiens 0 2329
ENST00000546160 PDE4D-201 protein_coding Homo_sapiens 0 2470

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