C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381395 IGF2-003 ENSG00000167244 9606 - 11:2129112-2137290 protein_coding

Homo sapiens EnsemblGRCh38

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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381395
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381395 124.739±0.00 19.691±0.00 0.766±0.00 3.926±3.60 1.563±0.00 22.793±0.00 18.241±0.00 117.735±0.00 10.184±9.37 12.797±10.67 208.692±255.20 1069.690±368.14 150.040±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0001 VISTA 11:1663842-2266142
CIL_0007RG CIL_0007RG_0001 VISTA 11:1668349-2271510
CIL_00097V CIL_00097V_0001 VISTA 11:1688064-2293510
CIL_0005N8 CIL_0005N8_0002 CGP 11:1947278-2149603
CIL_0009BT CIL_0009BT_0001 VISTA 11:2074187-2675527

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0002576 TAS platelet degranulation
GO:0005158 IPI insulin receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0006006 IEA glucose metabolic process
GO:0006349 TAS regulation of gene expression by genetic imprinting
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0007275 TAS multicellular organismal development
GO:0007596 TAS blood coagulation
GO:0008083 IDA growth factor activity
GO:0008284 IC positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0030168 TAS platelet activation
GO:0030546 ISS receptor activator activity
GO:0031093 TAS platelet alpha granule lumen
GO:0038028 ISS insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0042104 IDA positive regulation of activated T cell proliferation
GO:0043085 ISS positive regulation of catalytic activity
GO:0043410 IDA positive regulation of MAPK cascade
GO:0043539 ISS protein serine/threonine kinase activator activity
GO:0044267 TAS cellular protein metabolic process
GO:0045725 ISS positive regulation of glycogen biosynthetic process
GO:0045840 IDA positive regulation of mitosis
GO:0046628 IDA positive regulation of insulin receptor signaling pathway
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0051781 IEA positive regulation of cell division
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome
GO:2000467 ISS positive regulation of glycogen (starch) synthase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000033 Igf2-001 protein_coding Mus_musculus 0 697
ENSMUST00000097936 Igf2-201 protein_coding Mus_musculus 0 669
ENSMUST00000105936 Igf2-003 protein_coding Mus_musculus 0 662
ENSMUST00000121128 Igf2-002 protein_coding Mus_musculus 0 662
ENSMUST00000105935 Igf2-004 protein_coding Mus_musculus 0 627
ENSMUST00000145896 Igf2-005 protein_coding Mus_musculus 0 379

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