Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	furin (paired basic amino acid cleaving enzyme)
ENSMUST00000122232	Furin-001	ENSMUSG00000030530	10090	-	7:80389194-80402762	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Muscle	Ovary	Placenta	Testis
ENSMUST00000122232	4.098±0.00	42.017±11.48	8.001±0.63	5.407±0.00	9.072±3.73	11.159±4.82	6.900±0.90	16.343±2.81	10.900±8.68	10.637±1.70	14.604±4.09	19.085±11.43	0.429±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0008AY	CIL_0008AY_0002	VISTA	7:80145068-80746500

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004252	IBA	serine-type endopeptidase activity
GO:0005515	IPI	protein binding
GO:0005576	TAS	extracellular region
GO:0005615	IBA	extracellular space
GO:0005769	TAS	early endosome
GO:0005788	TAS	endoplasmic reticulum lumen
GO:0005794	IBA	Golgi apparatus
GO:0005886	IEA	plasma membrane
GO:0006508	IBA:IEA	proteolysis
GO:0008233	ISO	peptidase activity
GO:0009966	IDA	regulation of signal transduction
GO:0012510	TAS	trans-Golgi network transport vesicle membrane
GO:0016021	TAS	integral component of membrane
GO:0016485	ISO	protein processing
GO:0030140	ISO	trans-Golgi network transport vesicle
GO:0046872	IEA	metal ion binding

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENST00000268171	FURIN-001	protein_coding	Homo_sapiens	0	3463
ENST00000558794	FURIN-002	nonsense_mediated_decay	Homo_sapiens	0	830
ENST00000559353	FURIN-003	protein_coding	Homo_sapiens	0	420
ENST00000560824	FURIN-005	protein_coding	Homo_sapiens	0	671
ENST00000610579	FURIN-201	protein_coding	Homo_sapiens	0	3535
ENST00000618099	FURIN-202	protein_coding	Homo_sapiens	0	3463

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