C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin degrading enzyme
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000131070 Ide-001 ENSMUSG00000056999 10090 - 19:37268743-37330613 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000131070
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000131070 5.389±0.00 5.656±2.08 3.679±1.18 4.981±1.98 1.529±0.64 4.556±0.00 6.327±0.00 2.643±0.73 1.991±0.00 9.174±3.05 13.480±10.17 6.472±2.28 16.945±6.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VX CIL_0007VX_0002 VISTA 19:37192022-37797349
CIL_00018P CIL_00018P_0002 CGP 19:37207543-37337852
CIL_00018U CIL_00018U_0002 CGP 19:37268743-37421859

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001540 IEA beta-amyloid binding
GO:0001948 IEA glycoprotein binding
GO:0004222 IEA metalloendopeptidase activity
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005777 IEA peroxisome
GO:0005782 IEA peroxisomal matrix
GO:0005829 IEA cytosol
GO:0006200 IEA ATP catabolic process
GO:0006508 IEA proteolysis
GO:0008270 IEA zinc ion binding
GO:0008340 IEA determination of adult lifespan
GO:0009986 IEA cell surface
GO:0010815 IEA bradykinin catabolic process
GO:0010992 IEA ubiquitin homeostasis
GO:0016887 IEA ATPase activity
GO:0017046 IEA peptide hormone binding
GO:0031597 IEA cytosolic proteasome complex
GO:0031626 IEA beta-endorphin binding
GO:0032461 IEA positive regulation of protein oligomerization
GO:0042277 IEA peptide binding
GO:0042447 IEA hormone catabolic process
GO:0042803 IEA protein homodimerization activity
GO:0043130 IEA ubiquitin binding
GO:0043559 IEA insulin binding
GO:0044257 IEA cellular protein catabolic process
GO:0045861 IEA negative regulation of proteolysis
GO:0050435 IEA beta-amyloid metabolic process
GO:0051260 IEA protein homooligomerization
GO:0051289 IEA protein homotetramerization
GO:0051291 IEA protein heterooligomerization
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:1901142 IEA insulin metabolic process
GO:1901143 IEA insulin catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265986 IDE-001 protein_coding Homo_sapiens 0 3814
ENST00000371581 IDE-201 protein_coding Homo_sapiens 0 2250
ENST00000436178 IDE-007 protein_coding Homo_sapiens 0 806
ENST00000462988 IDE-004 processed_transcript Homo_sapiens 0 294
ENST00000463640 IDE-005 processed_transcript Homo_sapiens 0 257
ENST00000478361 IDE-002 nonsense_mediated_decay Homo_sapiens 0 1940
ENST00000492362 IDE-006 processed_transcript Homo_sapiens 0 375
ENST00000496903 IDE-003 processed_transcript Homo_sapiens 0 1821

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