C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mutL homolog 1 (E. coli)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000135695 Mlh1-006 ENSMUSG00000032498 10090 - 9:111249223-111261543 nonsense_mediated_decay

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000289 IMP nuclear-transcribed mRNA poly(A) tail shortening
GO:0000712 IMP resolution of meiotic recombination intermediates
GO:0000793 IDA condensed chromosome
GO:0000794 IDA condensed nuclear chromosome
GO:0000795 IDA synaptonemal complex
GO:0001673 IDA male germ cell nucleus
GO:0002204 IGI somatic recombination of immunoglobulin genes involved in immune response
GO:0003697 IBA single-stranded DNA binding
GO:0005694 IDA chromosome
GO:0005712 IDA chiasma
GO:0006200 IBA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006298 IMP mismatch repair
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0006974 IGI cellular response to DNA damage stimulus
GO:0007060 IMP male meiosis chromosome segregation
GO:0007126 TAS meiotic nuclear division
GO:0007129 IMP synapsis
GO:0007131 IMP reciprocal meiotic recombination
GO:0007140 IMP male meiosis
GO:0007283 IMP spermatogenesis
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016447 IMP somatic recombination of immunoglobulin gene segments
GO:0016887 IBA ATPase activity
GO:0032137 IGI guanine/thymine mispair binding
GO:0032389 IDA MutLalpha complex
GO:0043060 IMP meiotic metaphase I plate congression
GO:0043566 IDA structure-specific DNA binding
GO:0045132 IMP meiotic chromosome segregation
GO:0045190 IMP isotype switching
GO:0045950 IMP negative regulation of mitotic recombination
GO:0048477 IMP oogenesis
GO:0051257 IMP spindle midzone assembly involved in meiosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000231790 MLH1-001 protein_coding Homo_sapiens 0 477
ENST00000432299 MLH1-002 nonsense_mediated_decay Homo_sapiens 0 195
ENST00000435176 MLH1-006 protein_coding Homo_sapiens 0 477
ENST00000441265 MLH1-020 protein_coding Homo_sapiens 0 477
ENST00000442249 MLH1-013 nonsense_mediated_decay Homo_sapiens 2e-27 126
ENST00000455445 MLH1-005 protein_coding Homo_sapiens 0 477
ENST00000456676 MLH1-003 protein_coding Homo_sapiens 0 477
ENST00000457004 MLH1-012 nonsense_mediated_decay Homo_sapiens 0 283
ENST00000458009 MLH1-008 nonsense_mediated_decay Homo_sapiens 0 311
ENST00000458205 MLH1-004 protein_coding Homo_sapiens 0 477
ENST00000536378 MLH1-201 protein_coding Homo_sapiens 0 477
ENST00000539477 MLH1-202 protein_coding Homo_sapiens 0 477

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