C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mutL homolog 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000231790 MLH1-001 ENSG00000076242 9606 + 3:36993332-37050918 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000231790
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000231790 1.311±0.00 1.807±0.82 4.664±0.00 3.191±0.00 2.609±0.76 1.071±0.07 5.527±0.00 2.057±0.00 4.759±0.00 3.667±0.69 4.867±1.13 8.562±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00041G CIL_00041G_0002 CGP 3:36993332-37183689

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000289 IEA nuclear-transcribed mRNA poly(A) tail shortening
GO:0000712 IEA resolution of meiotic recombination intermediates
GO:0000793 IEA condensed chromosome
GO:0000794 IEA condensed nuclear chromosome
GO:0000795 IBA synaptonemal complex
GO:0001673 IEA male germ cell nucleus
GO:0002204 IEA somatic recombination of immunoglobulin genes involved in immune response
GO:0003697 IDA single-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005712 IBA chiasma
GO:0006200 IBA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006298 IGI:IEA mismatch repair
GO:0006303 IEA double-strand break repair via nonhomologous end joining
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007060 IEA male meiosis chromosome segregation
GO:0007129 IEA synapsis
GO:0007131 IEA reciprocal meiotic recombination
GO:0007140 IEA male meiosis
GO:0007283 IEA spermatogenesis
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IDA membrane
GO:0016446 IBA somatic hypermutation of immunoglobulin genes
GO:0016447 IEA somatic recombination of immunoglobulin gene segments
GO:0016887 IBA ATPase activity
GO:0030983 IEA mismatched DNA binding
GO:0032137 IEA guanine/thymine mispair binding
GO:0032389 IBA MutLalpha complex
GO:0032407 IDA MutSalpha complex binding
GO:0043060 IEA meiotic metaphase I plate congression
GO:0043566 IEA structure-specific DNA binding
GO:0045132 IEA meiotic chromosome segregation
GO:0045190 IEA isotype switching
GO:0045950 IEA negative regulation of mitotic recombination
GO:0048477 IEA oogenesis
GO:0051257 IEA spindle midzone assembly involved in meiosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035079 Mlh1-001 protein_coding Mus_musculus 0 2571
ENSMUST00000123869 Mlh1-003 retained_intron Mus_musculus 0 2061
ENSMUST00000135218 Mlh1-002 retained_intron Mus_musculus 0 1384
ENSMUST00000134316 Mlh1-005 processed_transcript Mus_musculus 0 717
ENSMUST00000135695 Mlh1-006 nonsense_mediated_decay Mus_musculus 0 477
ENSMUST00000128795 Mlh1-004 retained_intron Mus_musculus 0 215

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