C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor 2 (basic)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000608478 FGF2-002 ENSG00000138685 9606 + 4:122826831-122895464 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartENST00000608478
Transcript ID Heart
ENST00000608478 0.348±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YN CIL_0006YN_0002 CGP 4:122826708-122922968

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0001658 IDA branching involved in ureteric bud morphogenesis
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0002042 IDA cell migration involved in sprouting angiogenesis
GO:0005104 IPI fibroblast growth factor receptor binding
GO:0005125 IDA cytokine activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 TAS extracellular space
GO:0005634 IEA nucleus
GO:0006661 IDA phosphatidylinositol biosynthetic process
GO:0006935 TAS chemotaxis
GO:0007165 NAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007265 TAS Ras protein signal transduction
GO:0007399 TAS nervous system development
GO:0008083 IDA:IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IPI fibroblast growth factor receptor signaling pathway
GO:0009887 TAS organ morphogenesis
GO:0010764 IDA negative regulation of fibroblast migration
GO:0010863 IDA positive regulation of phospholipase C activity
GO:0030198 TAS extracellular matrix organization
GO:0030214 IDA hyaluronan catabolic process
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0032958 IDA inositol phosphate biosynthetic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042056 IDA chemoattractant activity
GO:0042060 TAS wound healing
GO:0042660 IDA positive regulation of cell fate specification
GO:0043536 IDA positive regulation of blood vessel endothelial cell migration
GO:0043537 IDA negative regulation of blood vessel endothelial cell migration
GO:0043552 IDA positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 TAS innate immune response
GO:0045765 TAS regulation of angiogenesis
GO:0045766 IDA positive regulation of angiogenesis
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048598 TAS embryonic morphogenesis
GO:0050918 IDA positive chemotaxis
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0051781 IEA positive regulation of cell division
GO:0060045 IDA positive regulation of cardiac muscle cell proliferation
GO:0060548 IDA negative regulation of cell death
GO:0060591 IDA chondroblast differentiation
GO:0061045 IDA negative regulation of wound healing
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038885 Fgf2-007 protein_coding Mus_musculus 0 599
ENSMUST00000138563 Fgf2-001 protein_coding Mus_musculus 0 599
ENSMUST00000108120 Fgf2-004 protein_coding Mus_musculus 0 412
ENSMUST00000091203 Fgf2-005 protein_coding Mus_musculus 0 409
ENSMUST00000145228 Fgf2-003 processed_transcript Mus_musculus 0 409
ENSMUST00000150021 Fgf2-002 processed_transcript Mus_musculus 0 409
ENSMUST00000138710 Fgf2-006 processed_transcript Mus_musculus 0 272

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