C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor 2 (basic)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264498 FGF2-001 ENSG00000138685 9606 + 4:122826708-122898236 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264498
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264498 2.696±0.00 0.844±0.00 0.595±0.00 1.801±0.37 2.849±1.07 1.743±0.77 0.394±0.15 0.649±0.29 1.224±1.10 1.551±0.51 0.174±0.10 0.791±0.52 0.576±0.08 0.613±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YN CIL_0006YN_0002 CGP 4:122826708-122922968

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001525 IEA angiogenesis
GO:0001759 IEA organ induction
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0007568 IEA aging
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008543 IEA fibroblast growth factor receptor signaling pathway
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0010001 IEA glial cell differentiation
GO:0010595 IEA positive regulation of endothelial cell migration
GO:0010628 IEA positive regulation of gene expression
GO:0021762 IEA substantia nigra development
GO:0021940 IEA positive regulation of cerebellar granule cell precursor proliferation
GO:0030324 IEA lung development
GO:0042060 IEA wound healing
GO:0045597 IEA positive regulation of cell differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045766 IEA positive regulation of angiogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046668 IEA regulation of retinal cell programmed cell death
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0048678 IEA response to axon injury
GO:0048864 IEA stem cell development
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051726 IEA regulation of cell cycle
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060128 IEA corticotropin hormone secreting cell differentiation
GO:0060129 IEA thyroid-stimulating hormone-secreting cell differentiation
GO:0060644 IEA mammary gland epithelial cell differentiation
GO:0060978 IEA angiogenesis involved in coronary vascular morphogenesis
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000038885 Fgf2-007 protein_coding Mus_musculus 0 599
ENSMUST00000138563 Fgf2-001 protein_coding Mus_musculus 0 599
ENSMUST00000108120 Fgf2-004 protein_coding Mus_musculus 0 412
ENSMUST00000091203 Fgf2-005 protein_coding Mus_musculus 0 409
ENSMUST00000145228 Fgf2-003 processed_transcript Mus_musculus 0 409
ENSMUST00000150021 Fgf2-002 processed_transcript Mus_musculus 0 409
ENSMUST00000138710 Fgf2-006 processed_transcript Mus_musculus 0 272

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