C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingosine kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000141798 Sphk1-007 ENSMUSG00000061878 10090 + 11:116534740-116536670 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000141798
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000141798 3.121±1.04 0.762±0.19 4.320±0.32 0.437±0.08 1.519±0.66 1.919±0.60 0.689±0.15 2.478±0.61 5.772±5.27 8.631±1.26 0.093±0.00 5.746±2.47 1.024±0.74 0.549±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WF CIL_0008WF_0002 VISTA 11:116019003-116619995
CIL_00009I CIL_00009I_0002 CGP 11:116470845-116536674
CIL_00079O CIL_00079O_0002 CGP 11:116530925-116581447

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0001568 IGI blood vessel development
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0001956 IEA positive regulation of neurotransmitter secretion
GO:0003677 ISA DNA binding
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005515 IEA protein binding
GO:0005516 ISA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IEA cytosol
GO:0005886 ISS plasma membrane
GO:0006670 ISS sphingosine metabolic process
GO:0006954 IMP inflammatory response
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IGI brain development
GO:0007565 IEA female pregnancy
GO:0008021 IEA synaptic vesicle
GO:0008284 IGI positive regulation of cell proliferation
GO:0008481 ISA sphinganine kinase activity
GO:0009267 IEA cellular response to starvation
GO:0010803 ISS regulation of tumor necrosis factor-mediated signaling pathway
GO:0010976 IEA positive regulation of neuron projection development
GO:0014070 IEA response to organic cyclic compound
GO:0014075 IEA response to amine
GO:0017050 ISS D-erythro-sphingosine kinase activity
GO:0019371 IEA cyclooxygenase pathway
GO:0019722 IEA calcium-mediated signaling
GO:0030307 IEA positive regulation of cell growth
GO:0030335 IEA positive regulation of cell migration
GO:0030424 IEA axon
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0032026 IEA response to magnesium ion
GO:0032570 IEA response to progesterone
GO:0032651 IMP regulation of interleukin-1 beta production
GO:0033198 IEA response to ATP
GO:0042346 ISS positive regulation of NF-kappaB import into nucleus
GO:0043005 IEA neuron projection
GO:0043066 IEA negative regulation of apoptotic process
GO:0045766 IEA positive regulation of angiogenesis
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045987 IEA positive regulation of smooth muscle contraction
GO:0046834 IEA lipid phosphorylation
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051721 IEA protein phosphatase 2A binding
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0070555 IEA response to interleukin-1
GO:0071363 IEA cellular response to growth factor stimulus

Homologs

No Homologs available.

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