C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000143517 Map2k2-001 ENSMUSG00000035027 10090 + 10:81105915-81124697 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000143517
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000143517 6.880±1.03 7.830±0.52 16.176±0.86 7.600±0.74 12.865±1.16 3.372±0.76 9.312±0.91 7.168±1.64 7.264±0.64 10.227±1.27 10.590±1.37 8.724±1.83 7.831±1.30

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 TAS activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IEA MAP kinase kinase activity
GO:0004712 TAS protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005778 IEA peroxisomal membrane
GO:0005783 IEA endoplasmic reticulum
GO:0005794 TAS Golgi apparatus
GO:0005829 TAS cytosol
GO:0005874 IEA microtubule
GO:0005911 IEA cell-cell junction
GO:0005925 TAS focal adhesion
GO:0005938 IEA cell cortex
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030165 IEA PDZ domain binding
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0032947 IDA protein complex scaffold
GO:0036289 IEA peptidyl-serine autophosphorylation
GO:0043539 IEA protein serine/threonine kinase activator activity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity
GO:0090170 TAS regulation of Golgi inheritance
GO:0097110 IEA scaffold protein binding
GO:2000147 IDA positive regulation of cell motility
GO:2000641 TAS regulation of early endosome to late endosome transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262948 MAP2K2-001 protein_coding Homo_sapiens 0 1421
ENST00000394867 MAP2K2-201 protein_coding Homo_sapiens 0 1277
ENST00000467614 RP11-286H14.4-001 transcribed_processed_pseudogene Homo_sapiens 0 1249
ENST00000593364 MAP2K2-005 processed_transcript Homo_sapiens 0 525
ENST00000597008 MAP2K2-007 retained_intron Homo_sapiens 0 329
ENST00000597263 MAP2K2-011 processed_transcript Homo_sapiens 0 241
ENST00000599345 MAP2K2-009 processed_transcript Homo_sapiens 0 267
ENST00000601786 MAP2K2-003 retained_intron Homo_sapiens 0 819
ENST00000602167 MAP2K2-008 processed_transcript Homo_sapiens 0 331

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