Transcript ID | Breast | Colon | Ovary |
---|---|---|---|
ENSMUST00000145118 | 4.189±0.21 | 2.242±0.00 | 8.590±5.56 |
Transcript Info |
||||||
Description: | a disintegrin and metallopeptidase domain 17 | |||||
---|---|---|---|---|---|---|
Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENSMUST00000145118 | Adam17-007 | ENSMUSG00000052593 | 10090 | - | 12:21323517-21373593 | nonsense_mediated_decay |
Expression Patterns
|
Conserved Regions | |||
---|---|---|---|
Region ID | Sub-Region | Region Type | Position |
CIL_00057M | CIL_00057M_0002 | CGP | 12:21286297-21323605 |
CIL_0007AU | CIL_0007AU_0003 | CGP | 12:21316392-21373632 |
CIL_0001MI | CIL_0001MI_0002 | CGP | 12:21323509-21417637 |
Gene Ontology | ||
---|---|---|
GO ID | Evidence Type | GO Description |
GO:0002467 | IMP | germinal center formation |
GO:0004222 | TAS | metalloendopeptidase activity |
GO:0005112 | ISS | Notch binding |
GO:0005515 | IPI | protein binding |
GO:0005576 | TAS | extracellular region |
GO:0005737 | IDA | cytoplasm |
GO:0005886 | TAS | plasma membrane |
GO:0006508 | ISS | proteolysis |
GO:0006509 | IMP | membrane protein ectodomain proteolysis |
GO:0007219 | IEA | Notch signaling pathway |
GO:0007220 | ISS | Notch receptor processing |
GO:0008237 | IDA | metallopeptidase activity |
GO:0008270 | IEA | zinc ion binding |
GO:0017124 | IEA | SH3 domain binding |
GO:0030183 | IMP | B cell differentiation |
GO:0030511 | IMP | positive regulation of transforming growth factor beta receptor signaling pathway |
GO:0033025 | IMP | regulation of mast cell apoptotic process |
GO:0033077 | IMP | T cell differentiation in thymus |
GO:0042493 | IMP | response to drug |
GO:0048536 | IMP | spleen development |
GO:0048870 | IMP | cell motility |
GO:0051088 | IDA | PMA-inducible membrane protein ectodomain proteolysis |
GO:0051272 | IMP | positive regulation of cellular component movement |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSDART00000135391 | adam17b-201 | protein_coding | Danio_rerio | 1e-38 | 167 |
ENSDART00000153339 | adam17b-001 | protein_coding | Danio_rerio | 1e-38 | 167 |
ENST00000310823 | ADAM17-001 | protein_coding | Homo_sapiens | 0 | 2848 |
ENST00000470914 | IAH1-001 | protein_coding | Homo_sapiens | 2.00386e-43 | 182 |
ENST00000478059 | ADAM17-002 | retained_intron | Homo_sapiens | 0 | 695 |
ENST00000484826 | IAH1-014 | retained_intron | Homo_sapiens | 0.00000002 | 64 |
ENST00000497134 | ADAM17-003 | protein_coding | Homo_sapiens | 0 | 942 |
ENST00000497473 | IAH1-003 | protein_coding | Homo_sapiens | 9.94922e-44 | 182 |
ENST00000618923 | ADAM17-201 | protein_coding | Homo_sapiens | 0 | 896 |