C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MKL (megakaryoblastic leukemia)/myocardin-like 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000149582 Mkl1-001 ENSMUSG00000042292 10090 - 15:81012281-81190757 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000149582
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000149582 4.657±1.07 4.816±3.04 5.641±0.97 11.433±4.63 6.804±2.97 14.194±4.59 1.289±0.12 3.072±0.98 1.511±0.64 7.572±0.72 2.994±1.79 7.653±2.31 4.610±2.30 9.652±3.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005W1 CIL_0005W1_0002 CGP 15:80977765-81190757
CIL_0005W2 CIL_0005W2_0002 CGP 15:81012281-81238963

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003779 IDA actin binding
GO:0003785 IDA actin monomer binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0010735 ISS positive regulation of transcription via serum response element binding
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:2001234 IDA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000355630 MKL1-001 protein_coding Homo_sapiens 0 3164
ENST00000396617 MKL1-201 protein_coding Homo_sapiens 0 3123
ENST00000402042 MKL1-002 protein_coding Homo_sapiens 0 1962
ENST00000402630 MKL1-009 protein_coding Homo_sapiens 0 512
ENST00000407029 MKL1-003 protein_coding Homo_sapiens 0 2795
ENST00000422851 MKL1-006 protein_coding Homo_sapiens 0 276
ENST00000463769 MKL1-004 processed_transcript Homo_sapiens 0 556
ENST00000466278 MKL1-005 processed_transcript Homo_sapiens 0 372
ENST00000614754 MKL1-202 protein_coding Homo_sapiens 0 2654
ENST00000618196 MKL1-203 protein_coding Homo_sapiens 0 2795
ENST00000618417 MKL1-204 protein_coding Homo_sapiens 0 553
ENST00000620651 MKL1-205 protein_coding Homo_sapiens 0 1962

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