C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: eukaryotic translation initiation factor 2 alpha kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000162950 Eif2ak3-002 ENSMUSG00000031668 10090 + 6:70844553-70864825 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonOvaryENSMUST00000162950
Transcript ID Adrenal Breast Colon Ovary
ENSMUST00000162950 7.753±4.20 5.446±0.66 5.526±1.37 5.756±1.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004QR CIL_0004QR_0002 CGP 6:70765720-70905245

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001503 ISS ossification
GO:0002063 IMP chondrocyte development
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004694 ISS eukaryotic translation initiation factor 2alpha kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006412 IDA translation
GO:0006468 IMP protein phosphorylation
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006983 ISS ER overload response
GO:0007029 IMP endoplasmic reticulum organization
GO:0007595 IMP lactation
GO:0009967 IDA positive regulation of signal transduction
GO:0010629 IMP negative regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0017148 IMP negative regulation of translation
GO:0019217 IMP regulation of fatty acid metabolic process
GO:0019722 IMP calcium-mediated signaling
GO:0030282 IMP bone mineralization
GO:0030968 ISS endoplasmic reticulum unfolded protein response
GO:0031016 IMP pancreas development
GO:0031018 ISS endocrine pancreas development
GO:0031642 IMP negative regulation of myelination
GO:0032092 IMP positive regulation of protein binding
GO:0032933 IDA SREBP signaling pathway
GO:0043066 IMP negative regulation of apoptotic process
GO:0045444 IDA fat cell differentiation
GO:0046777 ISS protein autophosphorylation
GO:0048009 IMP insulin-like growth factor receptor signaling pathway
GO:0051260 ISS protein homooligomerization
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1902237 IGI positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Homologs

No Homologs available.

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