C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: synuclein, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000163779 Snca-202 ENSMUSG00000025889 10090 - 6:60731573-60829855 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000163779
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000163779 0.380±0.18 0.306±0.14 0.276±0.06 15.778±12.15 0.532±0.19 0.405±0.17 3.028±1.56 0.990±0.44 0.326±0.08 3.097±1.16 0.191±0.06 0.549±0.29 0.378±0.00 0.127±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000KO CIL_0000KO_0002 CGP 6:60731573-60989378

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001774 IMP microglial cell activation
GO:0001956 IDA positive regulation of neurotransmitter secretion
GO:0001963 IMP synaptic transmission, dopaminergic
GO:0005507 ISS copper ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 IDA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0006631 IMP fatty acid metabolic process
GO:0006638 IMP neutral lipid metabolic process
GO:0006644 IMP phospholipid metabolic process
GO:0007006 IMP mitochondrial membrane organization
GO:0007268 IGI synaptic transmission
GO:0008344 IGI adult locomotory behavior
GO:0014048 IMP regulation of glutamate secretion
GO:0014059 IGI regulation of dopamine secretion
GO:0016234 IDA inclusion body
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0034599 IMP cellular response to oxidative stress
GO:0040012 IMP regulation of locomotion
GO:0042393 IDA histone binding
GO:0042416 IMP dopamine biosynthetic process
GO:0042417 IGI dopamine metabolic process
GO:0042493 IMP response to drug
GO:0042775 IMP mitochondrial ATP synthesis coupled electron transport
GO:0042802 IDA identical protein binding
GO:0043030 IMP regulation of macrophage activation
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0045202 IDA synapse
GO:0046928 IMP regulation of neurotransmitter secretion
GO:0048168 IMP regulation of neuronal synaptic plasticity
GO:0048169 IMP regulation of long-term neuronal synaptic plasticity
GO:0048488 IMP synaptic vesicle endocytosis
GO:0048489 IMP synaptic vesicle transport
GO:0050544 IDA arachidonic acid binding
GO:0050806 IMP positive regulation of synaptic transmission
GO:0050808 IGI synapse organization
GO:0050812 IMP regulation of acyl-CoA biosynthetic process
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060291 IMP long-term synaptic potentiation
GO:0061024 IMP membrane organization
GO:2000377 IMP regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336904 SNCA-003 protein_coding Homo_sapiens 0 1007
ENST00000345009 SNCA-005 protein_coding Homo_sapiens 0 473
ENST00000394986 SNCA-001 protein_coding Homo_sapiens 0 1007
ENST00000394989 SNCA-201 protein_coding Homo_sapiens 0 765
ENST00000394991 SNCA-002 protein_coding Homo_sapiens 0 1007
ENST00000420646 SNCA-202 protein_coding Homo_sapiens 0 473
ENST00000502987 SNCA-009 protein_coding Homo_sapiens 0 451
ENST00000505199 SNCA-004 protein_coding Homo_sapiens 0 340
ENST00000506244 SNCA-006 protein_coding Homo_sapiens 0 593
ENST00000506691 SNCA-007 protein_coding Homo_sapiens 0 315
ENST00000508895 SNCA-008 protein_coding Homo_sapiens 0 859
ENST00000611107 SNCA-010 protein_coding Homo_sapiens 0 209
ENST00000618500 SNCA-203 protein_coding Homo_sapiens 0 765

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