C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-akt murine thymoma viral oncogene homolog 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392038 AKT2-001 ENSG00000105221 9606 - 19:40230317-40285395 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyOvaryPlacentaTestisENST00000392038
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Ovary Placenta Testis
ENST00000392038 2.841±0.00 3.934±0.00 1.964±0.00 8.295±0.00 3.466±0.00 0.537±0.00 2.715±2.02 8.996±0.56 2.544±0.62 6.569±1.42

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0005938 ISS cell cortex
GO:0005978 IEA glycogen biosynthetic process
GO:0006006 IEA glucose metabolic process
GO:0006417 IEA regulation of translation
GO:0006464 TAS cellular protein modification process
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007165 TAS signal transduction
GO:0008286 IMP insulin receptor signaling pathway
GO:0008643 IEA carbohydrate transport
GO:0010748 IMP negative regulation of plasma membrane long-chain fatty acid transport
GO:0010907 IMP positive regulation of glucose metabolic process
GO:0016301 TAS kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030334 TAS regulation of cell migration
GO:0031340 ISS positive regulation of vesicle fusion
GO:0032000 IMP positive regulation of fatty acid beta-oxidation
GO:0032287 IEA peripheral nervous system myelin maintenance
GO:0032587 ISS ruffle membrane
GO:0032859 IEA activation of Ral GTPase activity
GO:0032869 IMP cellular response to insulin stimulus
GO:0045444 TAS fat cell differentiation
GO:0045725 IMP positive regulation of glycogen biosynthetic process
GO:0046326 IMP positive regulation of glucose import
GO:0060644 TAS mammary gland epithelial cell differentiation
GO:0061024 TAS membrane organization
GO:0065002 ISS intracellular protein transmembrane transport
GO:0071156 TAS regulation of cell cycle arrest
GO:0072659 IEA protein localization to plasma membrane
GO:0090314 ISS positive regulation of protein targeting to membrane
GO:2000147 IMP positive regulation of cell motility
GO:2001275 IEA positive regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108344 Akt2-001 protein_coding Mus_musculus 0 2193
ENSMUST00000167435 Akt2-201 protein_coding Mus_musculus 0 2117
ENSMUST00000051356 Akt2-003 protein_coding Mus_musculus 0 2013
ENSMUST00000108343 Akt2-002 protein_coding Mus_musculus 0 2013
ENSMUST00000120718 Akt2-ps-001 processed_pseudogene Mus_musculus 0 1869
ENSMUST00000085917 Akt2-013 protein_coding Mus_musculus 0 1114
ENSMUST00000136962 Akt2-009 protein_coding Mus_musculus 0 985
ENSMUST00000001780 Akt1-001 protein_coding Mus_musculus 0 965
ENSMUST00000136981 Akt2-012 retained_intron Mus_musculus 0 712
ENSMUST00000143347 Akt2-011 retained_intron Mus_musculus 0 671
ENSMUST00000108342 Akt2-005 protein_coding Mus_musculus 0 669
ENSMUST00000128540 Akt2-004 protein_coding Mus_musculus 0 496
ENSMUST00000142365 Akt2-010 protein_coding Mus_musculus 0 446
ENSMUST00000128300 Akt1-006 protein_coding Mus_musculus 0 405
ENSMUST00000138459 Akt2-006 protein_coding Mus_musculus 0 353
ENSMUST00000159815 Akt1-009 retained_intron Mus_musculus 0 300
ENSMUST00000143499 Akt2-008 protein_coding Mus_musculus 0 226
ENSMUST00000147263 Akt2-007 processed_transcript Mus_musculus 2e-32 147

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