C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: checkpoint kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000172702 Chek1-002 ENSMUSG00000032113 10090 - 9:36708482-36726374 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENSMUST00000172702
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENSMUST00000172702 0.052±0.00 0.212±0.07 0.100±0.00 0.116±0.07 0.071±0.00 0.145±0.05 0.086±0.01 0.059±0.00 0.109±0.07 0.570±0.45 0.537±0.00 0.268±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000086 IMP G2/M transition of mitotic cell cycle
GO:0000781 IEA chromosome, telomeric region
GO:0000785 IDA chromatin
GO:0000794 ISS condensed nuclear chromosome
GO:0004672 IMP protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IDA replication fork
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0006281 IDA DNA repair
GO:0006468 IDA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0006975 ISS DNA damage induced protein phosphorylation
GO:0010468 IGI regulation of gene expression
GO:0010569 ISS regulation of double-strand break repair via homologous recombination
GO:0010767 IMP regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0010972 IEA negative regulation of G2/M transition of mitotic cell cycle
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0031572 ISS G2 DNA damage checkpoint
GO:0035402 IDA histone kinase activity (H3-T11 specific)
GO:0035407 IDA histone H3-T11 phosphorylation
GO:0042127 IMP regulation of cell proliferation
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045839 ISS negative regulation of mitosis
GO:0046602 ISS regulation of mitotic centrosome separation
GO:0048096 IMP chromatin-mediated maintenance of transcription
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071310 IEA cellular response to organic substance
GO:0071313 IEA cellular response to caffeine
GO:2000279 IEA negative regulation of DNA biosynthetic process
GO:2000615 IDA regulation of histone H3-K9 acetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000278916 CHEK1-006 protein_coding Homo_sapiens 0 1349
ENST00000427383 CHEK1-001 protein_coding Homo_sapiens 0 1509
ENST00000428830 CHEK1-002 protein_coding Homo_sapiens 0 1786
ENST00000438015 CHEK1-201 protein_coding Homo_sapiens 0 1962
ENST00000498122 CHEK1-016 nonsense_mediated_decay Homo_sapiens 0 350
ENST00000524737 CHEK1-007 protein_coding Homo_sapiens 0 1803
ENST00000525396 CHEK1-018 nonsense_mediated_decay Homo_sapiens 0 571
ENST00000526937 CHEK1-010 protein_coding Homo_sapiens 0 715
ENST00000527013 CHEK1-011 protein_coding Homo_sapiens 0 863
ENST00000528276 CHEK1-015 retained_intron Homo_sapiens 0 859
ENST00000531062 CHEK1-014 retained_intron Homo_sapiens 0 250
ENST00000531607 CHEK1-012 protein_coding Homo_sapiens 0 564
ENST00000532449 CHEK1-202 protein_coding Homo_sapiens 0 1539
ENST00000532669 CHEK1-013 protein_coding Homo_sapiens 0 708
ENST00000533778 CHEK1-009 protein_coding Homo_sapiens 0 198
ENST00000534070 CHEK1-004 protein_coding Homo_sapiens 0 1962
ENST00000534685 CHEK1-008 protein_coding Homo_sapiens 0 534
ENST00000544373 CHEK1-005 protein_coding Homo_sapiens 0 1565

Loading