C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FMS-like tyrosine kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000176456 Flt3-003 ENSMUSG00000042817 10090 - 5:147330741-147400489 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000176456
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000176456 0.035±0.00 0.035±0.01 0.069±0.00 0.147±0.06 0.319±0.16 0.108±0.02 0.021±0.01 0.033±0.00 0.143±0.12 0.152±0.02 0.076±0.05 0.194±0.09 0.753±1.14 0.086±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CO CIL_0008CO_0002 VISTA 5:146855041-147456530
CIL_00082E CIL_00082E_0002 VISTA 5:146922660-147524221
CIL_0007MT CIL_0007MT_0002 UCNEbase 5:146994099-147547626
CIL_0000G8 CIL_0000G8_0003 CGP 5:147314984-147400489
CIL_0000G0 CIL_0000G0_0003 CGP 5:147330741-147548502

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IGI positive regulation of protein phosphorylation
GO:0002318 IMP myeloid progenitor cell differentiation
GO:0002320 IGI lymphoid progenitor cell differentiation
GO:0002328 IMP pro-B cell differentiation
GO:0002572 IMP pro-T cell differentiation
GO:0004713 IDA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008285 IMP negative regulation of cell proliferation
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030097 ISO hemopoiesis
GO:0030098 IDA lymphocyte differentiation
GO:0043548 IDA phosphatidylinositol 3-kinase binding
GO:0045578 IDA negative regulation of B cell differentiation
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000241453 FLT3-001 protein_coding Homo_sapiens 0 2754
ENST00000380987 FLT3-002 nonsense_mediated_decay Homo_sapiens 0 2076

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