C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: low density lipoprotein receptor-related protein 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000177294 Lrp5-004 ENSMUSG00000024913 10090 - 19:3584836-3615792 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000177294
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000177294 5.230±0.96 1.698±0.00 0.813±0.53 5.237±0.48 5.241±1.80 3.892±0.28 3.465±0.19 1.762±0.40 8.278±0.15 1.235±0.00 6.906±1.00 3.744±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001P1 CIL_0001P1_0002 CGP 19:3454933-3686564

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001702 IGI gastrulation with mouth forming second
GO:0001944 IMP vasculature development
GO:0002076 IMP osteoblast development
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005886 IBA plasma membrane
GO:0008203 IMP cholesterol metabolic process
GO:0009952 IGI anterior/posterior pattern specification
GO:0015026 IBA coreceptor activity
GO:0016055 IDA Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0030278 IBA regulation of ossification
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0035019 IMP somatic stem cell maintenance
GO:0035108 IGI limb morphogenesis
GO:0042074 IGI cell migration involved in gastrulation
GO:0042632 IBA cholesterol homeostasis
GO:0042733 IGI embryonic digit morphogenesis
GO:0042813 IDA Wnt-activated receptor activity
GO:0042981 IMP regulation of apoptotic process
GO:0043235 IBA receptor complex
GO:0044332 IBA Wnt signaling pathway involved in dorsal/ventral axis specification
GO:0045598 IBA regulation of fat cell differentiation
GO:0045944 IBA positive regulation of transcription from RNA polymerase II promoter
GO:0046849 IMP bone remodeling
GO:0046850 IMP regulation of bone remodeling
GO:0048539 IBA bone marrow development
GO:0048596 IBA embryonic camera-type eye morphogenesis
GO:0060033 IMP anatomical structure regression
GO:0060059 IBA embryonic retina morphogenesis in camera-type eye
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060349 IBA bone morphogenesis
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0060603 IGI mammary gland duct morphogenesis
GO:0060612 IBA adipose tissue development
GO:0060764 IMP cell-cell signaling involved in mammary gland development
GO:0061178 IMP regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061299 IMP retina vasculature morphogenesis in camera-type eye
GO:0061304 IBA retinal blood vessel morphogenesis
GO:1902262 IMP apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000294304 LRP5-001 protein_coding Homo_sapiens 0 3038
ENST00000528714 LRP5-003 processed_transcript Homo_sapiens 0 359
ENST00000529993 LRP5-002 nonsense_mediated_decay Homo_sapiens 0 3038

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