C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000215659 MAPK12-001 ENSG00000188130 9606 - 22:50252903-50261825 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyMuscleOvaryPlacentaTestisENST00000215659
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Muscle Ovary Placenta Testis
ENST00000215659 8.165±0.00 8.930±0.00 4.463±0.03 3.505±2.39 4.603±0.00 4.635±0.00 9.177±0.00 68.559±40.94 13.424±7.72 4.729±1.26 7.099±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000096 CIL_000096_0001 CGP 22:50217689-50251405
CIL_0006L4 CIL_0006L4_0001 CGP 22:50245183-50261825
CIL_00009B CIL_00009B_0001 CGP 22:50245450-50270767

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004707 IEA MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006975 TAS DNA damage induced protein phosphorylation
GO:0007050 TAS cell cycle arrest
GO:0007165 TAS signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007517 TAS muscle organ development
GO:0010952 NAS positive regulation of peptidase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0042692 TAS muscle cell differentiation
GO:0045445 IDA myoblast differentiation
GO:0045786 IEA negative regulation of cell cycle
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051149 TAS positive regulation of muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000088827 Mapk12-201 protein_coding Mus_musculus 0 1195
ENSMUST00000004986 Mapk13-001 protein_coding Mus_musculus 0 416
ENSMUST00000129096 Mapk13-002 nonsense_mediated_decay Mus_musculus 0 326
ENSMUST00000088823 Mapk11-201 protein_coding Mus_musculus 0 283

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