C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: peptidylprolyl isomerase F
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000225174 PPIF-001 ENSG00000108179 9606 + 10:79347478-79355337 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225174
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225174 8.543±0.00 16.167±0.00 2.476±0.00 11.256±9.00 6.888±6.18 8.045±6.47 22.809±19.99 27.947±18.94 38.917±0.00 7.083±6.91 4.523±1.70 20.952±15.96 25.054±2.10 21.567±7.99

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PL CIL_0008PL_0001 VISTA 10:78848267-79450832
CIL_0007WJ CIL_0007WJ_0001 VISTA 10:78920559-79524285
CIL_0001G8 CIL_0001G8_0001 CGP 10:79069035-79355337
CIL_0003H9 CIL_0003H9_0001 CGP 10:79347469-79445627

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0002931 ISS response to ischemia
GO:0003755 IEA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005753 ISS mitochondrial proton-transporting ATP synthase complex
GO:0005759 IEA mitochondrial matrix
GO:0006457 IEA protein folding
GO:0006979 IEA response to oxidative stress
GO:0008637 IEA apoptotic mitochondrial changes
GO:0010849 ISS regulation of proton-transporting ATPase activity, rotational mechanism
GO:0010939 IEA regulation of necrotic cell death
GO:0016018 IEA cyclosporin A binding
GO:0016020 TAS membrane
GO:0032780 ISS negative regulation of ATPase activity
GO:0042277 IEA peptide binding
GO:0042981 IEA regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0046902 ISS regulation of mitochondrial membrane permeability
GO:0070266 IEA necroptotic process
GO:0070301 IMP cellular response to hydrogen peroxide
GO:0071243 ISS cellular response to arsenic-containing substance
GO:0071277 ISS cellular response to calcium ion
GO:0090200 ISS positive regulation of release of cytochrome c from mitochondria
GO:0090201 IDA negative regulation of release of cytochrome c from mitochondria
GO:0090324 ISS negative regulation of oxidative phosphorylation
GO:1902445 IMP regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
GO:2000276 ISS negative regulation of oxidative phosphorylation uncoupler activity
GO:2001243 IMP negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022419 Ppif-001 protein_coding Mus_musculus 0 785
ENSMUST00000125881 Ppif-002 retained_intron Mus_musculus 0 366
ENSDART00000025620 ppiaa-001 protein_coding Danio_rerio 2e-33 148
ENSDART00000123878 ppiaa-002 protein_coding Danio_rerio 8e-32 143
ENSDART00000139986 ppiaa-004 retained_intron Danio_rerio 2e-28 132
ENSDART00000137036 ppiaa-003 retained_intron Danio_rerio 8e-22 110

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