C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukotriene A4 hydrolase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000228740 LTA4H-001 ENSG00000111144 9606 - 12:96000828-96035661 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228740
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228740 8.431±0.00 16.539±0.00 5.893±0.00 4.586±1.31 14.979±11.27 20.327±11.41 4.407±2.84 5.815±0.03 5.206±0.14 34.281±20.74 8.113±3.18 29.344±18.85 15.547±3.11 23.479±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AH CIL_0006AH_0002 CGP 12:96000828-96269835

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004177 IDA aminopeptidase activity
GO:0004301 TAS epoxide hydrolase activity
GO:0004463 IDA:IEA leukotriene-A4 hydrolase activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006508 IEA proteolysis
GO:0006691 TAS leukotriene metabolic process
GO:0006954 NAS inflammatory response
GO:0008233 TAS peptidase activity
GO:0008237 IEA metallopeptidase activity
GO:0008270 IDA:IEA zinc ion binding
GO:0019369 TAS arachidonic acid metabolic process
GO:0019370 IDA:IEA leukotriene biosynthetic process
GO:0043171 IDA peptide catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000016033 Lta4h-201 protein_coding Mus_musculus 0 2121
ENSMUST00000185902 RP24-304A3.1-001 processed_pseudogene Mus_musculus 0 520

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