C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000229328 PRKAB1-001 ENSG00000111725 9606 + 12:119667753-119681630 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000229328
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000229328 20.722±0.00 9.013±0.00 2.750±0.00 6.859±4.81 3.876±2.17 4.990±2.96 1.552±1.35 19.155±0.00 1.046±0.48 4.758±3.10 0.764±0.54 9.127±5.90 16.653±5.13 15.201±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G8 CIL_0007G8_0002 CGP 12:119593459-119681630

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004679 IEA AMP-activated protein kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006468 IDA protein phosphorylation
GO:0006633 IEA fatty acid biosynthetic process
GO:0007050 TAS cell cycle arrest
GO:0007165 TAS signal transduction
GO:0008286 TAS insulin receptor signaling pathway
GO:0010628 IDA positive regulation of gene expression
GO:0019901 IEA protein kinase binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0043234 IEA protein complex
GO:0050790 IEA regulation of catalytic activity
GO:0051291 IEA protein heterooligomerization
GO:0061024 TAS membrane organization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031486 Prkab1-001 protein_coding Mus_musculus 0 1037
ENSMUST00000111999 Prkab1-002 protein_coding Mus_musculus 0 1016
ENSMUST00000147343 Prkab1-005 retained_intron Mus_musculus 0 857
ENSMUST00000141018 Prkab1-007 retained_intron Mus_musculus 0 545
ENSMUST00000045743 Prkab2-001 protein_coding Mus_musculus 0 246
ENSMUST00000130924 Prkab2-003 nonsense_mediated_decay Mus_musculus 0 235
ENSMUST00000143927 Prkab2-002 nonsense_mediated_decay Mus_musculus 1e-36 159

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