C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T-box 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000240328 TBX2-001 ENSG00000121068 9606 + 17:61399896-61409425 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000240328
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000240328 2.415±0.00 3.993±0.00 0.840±0.00 0.907±0.82 4.830±4.30 1.250±0.65 2.421±1.82 27.848±0.00 1.800±0.00 21.734±19.55 1.181±0.51 5.457±1.89 47.700±5.74 4.047±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000703 CIL_000703_0001 CGP 17:60677453-61409466
CIL_0007RJ CIL_0007RJ_0001 VISTA 17:60951116-61552834
CIL_0007JV CIL_0007JV_0001 UCNEbase 17:61126460-61946035

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003007 IEA heart morphogenesis
GO:0003148 ISS outflow tract septum morphogenesis
GO:0003151 ISS outflow tract morphogenesis
GO:0003203 ISS endocardial cushion morphogenesis
GO:0003256 ISS regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 TAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007521 ISS muscle cell fate determination
GO:0007569 IDA cell aging
GO:0008284 IDA positive regulation of cell proliferation
GO:0035909 ISS aorta morphogenesis
GO:0036302 ISS atrioventricular canal development
GO:0042733 ISS embryonic digit morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048596 ISS embryonic camera-type eye morphogenesis
GO:0048738 ISS cardiac muscle tissue development
GO:0060021 IEA palate development
GO:0060045 ISS positive regulation of cardiac muscle cell proliferation
GO:0060465 ISS pharynx development
GO:0060560 IEA developmental growth involved in morphogenesis
GO:0060596 IEA mammary placode formation
GO:0090398 IDA cellular senescence
GO:1901208 ISS negative regulation of heart looping
GO:1901211 ISS negative regulation of cardiac chamber formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000095 Tbx2-001 protein_coding Mus_musculus 0 3164

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