C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: early growth response 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000242480 EGR2-001 ENSG00000122877 9606 - 10:62811996-62816355 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000242480
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000242480 0.614±0.00 0.916±0.00 0.440±0.00 0.400±0.00 5.623±0.00 0.143±0.00 0.198±0.09 0.429±0.00 0.565±0.12 3.068±2.23 0.902±0.28 1.958±1.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NR CIL_0002NR_0002 CGP 10:62804857-62919900
CIL_0004Q4 CIL_0004Q4_0002 CGP 10:62811996-63155031

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0003677 IEA DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006611 ISS protein export from nucleus
GO:0007420 TAS brain development
GO:0007422 TAS peripheral nervous system development
GO:0007611 IEA learning or memory
GO:0007622 IEA rhythmic behavior
GO:0008045 IEA motor neuron axon guidance
GO:0008219 IEA cell death
GO:0014037 IEA Schwann cell differentiation
GO:0016874 IEA ligase activity
GO:0016925 IEA protein sumoylation
GO:0021569 IEA rhombomere 3 development
GO:0021612 IEA facial nerve structural organization
GO:0021660 IEA rhombomere 3 formation
GO:0021666 IEA rhombomere 5 formation
GO:0030278 IEA regulation of ossification
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032868 IEA response to insulin
GO:0035284 IEA brain segmentation
GO:0035914 IBA skeletal muscle cell differentiation
GO:0042552 IBA myelination
GO:0043066 IBA negative regulation of apoptotic process
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045444 ISS fat cell differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048168 IBA regulation of neuronal synaptic plasticity
GO:0071310 IEA cellular response to organic substance
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000048289 Egr2-001 protein_coding Mus_musculus 0 2449
ENSMUST00000105438 Egr2-002 protein_coding Mus_musculus 0 1989
ENSMUST00000127820 Egr2-003 protein_coding Mus_musculus 0 1832
ENSMUST00000145936 Egr2-006 protein_coding Mus_musculus 0 965
ENSMUST00000145754 Egr2-005 protein_coding Mus_musculus 0 804
ENSMUST00000146986 Egr2-007 protein_coding Mus_musculus 0 433
ENSMUST00000035908 Egr3-201 protein_coding Mus_musculus 0 303
ENSMUST00000130933 Egr2-004 protein_coding Mus_musculus 0 289
ENSDART00000054460 egr1-001 protein_coding Danio_rerio 0 248

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