C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: egl-9 family hypoxia-inducible factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000250457 EGLN3-001 ENSG00000129521 9606 - 14:33924231-33951081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000250457
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000250457 2.533±0.00 4.448±0.00 1.312±0.00 4.335±1.06 1.301±0.71 2.483±1.19 9.990±6.80 0.730±0.48 3.359±3.27 0.938±0.12 1.248±0.66 2.420±1.19 10.813±4.56 0.997±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007M4 CIL_0007M4_0001 UCNEbase 14:32599473-34309899
CIL_0005RA CIL_0005RA_0002 CGP 14:32934933-34462774
CIL_0008MA CIL_0008MA_0001 VISTA 14:33353122-33953826
CIL_0008M9 CIL_0008M9_0001 VISTA 14:33432900-34033923
CIL_0009C2 CIL_0009C2_0001 VISTA 14:33616095-34217628
CIL_0005R9 CIL_0005R9_0002 CGP 14:33924231-34462774

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEP response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 IEP apoptotic process
GO:0006919 IEP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0016491 IEA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018126 IDA protein hydroxylation
GO:0018401 IDA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0031418 IEA L-ascorbic acid binding
GO:0031545 IDA peptidyl-proline 4-dioxygenase activity
GO:0042127 IEP regulation of cell proliferation
GO:0043523 ISS regulation of neuron apoptotic process
GO:0055114 IEA oxidation-reduction process
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039516 Egln3-001 protein_coding Mus_musculus 0 1162

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