C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DEXH (Asp-Glu-X-His) box polypeptide 58
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000251642 DHX58-001 ENSG00000108771 9606 - 17:42101404-42112733 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000251642
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000251642 3.193±0.00 3.223±0.00 1.193±0.00 1.758±0.00 0.681±0.00 2.093±0.00 0.251±0.00 3.044±0.00 2.427±0.57 3.418±0.37 2.832±0.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003J CIL_00003J_0001 CGP 17:42025576-42112733
CIL_0004GH CIL_0004GH_0001 CGP 17:42101404-42121358

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0003727 IDA single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0008152 IEA metabolic process
GO:0008270 IDA zinc ion binding
GO:0009615 ISS response to virus
GO:0016032 IEA viral process
GO:0016787 IEA hydrolase activity
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0032480 IDA negative regulation of type I interferon production
GO:0032481 ISS positive regulation of type I interferon production
GO:0039534 IMP negative regulation of MDA-5 signaling pathway
GO:0039536 IDA negative regulation of RIG-I signaling pathway
GO:0045087 IEA innate immune response
GO:0045088 IDA regulation of innate immune response
GO:0045824 IDA negative regulation of innate immune response
GO:0051607 IEA defense response to virus
GO:1900245 ISS positive regulation of MDA-5 signaling pathway
GO:1900246 ISS positive regulation of RIG-I signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000017974 Dhx58-001 protein_coding Mus_musculus 0 1546
ENSMUST00000132930 Dhx58-002 processed_transcript Mus_musculus 0 534
ENSMUST00000126167 Dhx58-003 processed_transcript Mus_musculus 0 516
ENSMUST00000150656 Dhx58-004 processed_transcript Mus_musculus 0 257

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