C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, muscarinic 3, cardiac
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000187510 Chrm3-001 ENSMUSG00000046159 10090 - 13:9875486-10360844 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000187510
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000187510 0.481±0.30 0.938±0.38 9.844±1.06 2.336±1.73 0.240±0.17 1.146±0.42 0.185±0.08 1.168±0.10 0.016±0.01 0.974±0.28 0.052±0.03 0.461±0.22 0.076±0.05 0.069±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LI CIL_0000LI_0002 CGP 13:9875486-12106945

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003056 IEA regulation of vascular smooth muscle contraction
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006939 IMP smooth muscle contraction
GO:0007207 TAS phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007213 ISS G-protein coupled acetylcholine receptor signaling pathway
GO:0007271 TAS synaptic transmission, cholinergic
GO:0007586 IMP digestion
GO:0008144 IEA drug binding
GO:0015464 TAS acetylcholine receptor activity
GO:0016907 ISS G-protein coupled acetylcholine receptor activity
GO:0019229 IEA regulation of vasoconstriction
GO:0030054 IEA cell junction
GO:0030425 IEA dendrite
GO:0032279 IEA asymmetric synapse
GO:0042166 ISS acetylcholine binding
GO:0043547 TAS positive regulation of GTPase activity
GO:0043679 IEA axon terminus
GO:0045211 IEA postsynaptic membrane
GO:0045987 IDA positive regulation of smooth muscle contraction
GO:0046541 IEA saliva secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000255380 CHRM3-001 protein_coding Homo_sapiens 0 2278
ENST00000448020 CHRM3-002 protein_coding Homo_sapiens 0 357
ENST00000468573 CHRM3-004 processed_transcript Homo_sapiens 0 239
ENST00000492335 CHRM3-006 processed_transcript Homo_sapiens 4e-25 119
ENST00000615928 CHRM3-201 protein_coding Homo_sapiens 0 2098

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