C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BLK proto-oncogene, Src family tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000259089 BLK-001 ENSG00000136573 9606 + 8:11494001-11564604 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonLiverLungOvaryTestisENST00000259089
Transcript ID Adipose Adrenal Breast Colon Liver Lung Ovary Testis
ENST00000259089 0.031±0.00 19.083±0.00 0.096±0.00 0.497±0.00 0.180±0.06 0.252±0.00 0.159±0.07 0.082±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Y4 CIL_0008Y4_0001 VISTA 8:11271783-11873892
CIL_000919 CIL_000919_0001 VISTA 8:11446673-12047186

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA:TAS protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032024 IMP positive regulation of insulin secretion
GO:0035556 TAS intracellular signal transduction
GO:0050853 IDA B cell receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000014597 Blk-201 protein_coding Mus_musculus 0 1513
ENSMUST00000171223 Fgr-201 protein_coding Mus_musculus 3e-32 145
ENSMUST00000138179 Fgr-002 processed_transcript Mus_musculus 3e-32 145
ENSMUST00000030693 Fgr-001 protein_coding Mus_musculus 3e-32 145

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