C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000030693 Fgr-001 ENSMUSG00000028874 10090 + 4:132974102-133001910 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030693 0.815±0.38 0.133±0.04 0.371±0.01 0.021±0.01 2.334±0.63 0.670±0.11 0.199±0.09 0.432±0.14 0.750±0.60 3.620±0.59 0.191±0.22 0.368±0.24 0.143±0.06 0.101±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WN CIL_0008WN_0002 VISTA 4:132816592-133418424

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001784 IDA phosphotyrosine binding
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005743 IEA mitochondrial inner membrane
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0007229 IMP integrin-mediated signaling pathway
GO:0008360 IMP regulation of cell shape
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015629 IDA actin cytoskeleton
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019901 IDA protein kinase binding
GO:0030335 IMP positive regulation of cell migration
GO:0032587 IDA ruffle membrane
GO:0032956 TAS regulation of actin cytoskeleton organization
GO:0034987 IDA immunoglobulin receptor binding
GO:0034988 IEA Fc-gamma receptor I complex binding
GO:0043306 IDA positive regulation of mast cell degranulation
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 IEA innate immune response
GO:0045088 IMP regulation of innate immune response
GO:0045859 IDA regulation of protein kinase activity
GO:0046777 IEA protein autophosphorylation
GO:0050715 IDA positive regulation of cytokine secretion
GO:0050764 IMP regulation of phagocytosis
GO:0050830 IGI defense response to Gram-positive bacterium
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000259089 BLK-001 protein_coding Homo_sapiens 3e-32 145
ENST00000374003 FGR-002 protein_coding Homo_sapiens 0 1509
ENST00000374004 FGR-004 protein_coding Homo_sapiens 0 1483
ENST00000374005 FGR-001 protein_coding Homo_sapiens 0 1513
ENST00000399173 FGR-201 protein_coding Homo_sapiens 0 1509
ENST00000457296 FGR-007 protein_coding Homo_sapiens 0 793
ENST00000468038 FGR-006 processed_transcript Homo_sapiens 6e-29 132
ENST00000475472 FGR-005 processed_transcript Homo_sapiens 4e-30 135
ENST00000526097 BLK-005 retained_intron Homo_sapiens 7e-22 110
ENST00000529894 BLK-004 protein_coding Homo_sapiens 2e-32 145

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