C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GTP cyclohydrolase I feedback regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000260447 GCHFR-001 ENSG00000137880 9606 + 15:40764020-40767710 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverENST00000260447
Transcript ID Kidney Liver
ENST00000260447 4.709±0.00 30.722±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070C CIL_00070C_0001 CGP 15:40735884-40767710
CIL_00070D CIL_00070D_0001 CGP 15:40764020-40807477

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004857 IEA enzyme inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006461 IEA protein complex assembly
GO:0006809 TAS nitric oxide biosynthetic process
GO:0008152 IEA metabolic process
GO:0009890 IEA negative regulation of biosynthetic process
GO:0016597 IEA amino acid binding
GO:0016787 IEA hydrolase activity
GO:0019899 IEA enzyme binding
GO:0030425 IDA dendrite
GO:0030742 IEA GTP-dependent protein binding
GO:0031965 IDA nuclear membrane
GO:0042133 TAS neurotransmitter metabolic process
GO:0042470 IDA melanosome
GO:0043105 IEA negative regulation of GTP cyclohydrolase I activity
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0044549 IEA GTP cyclohydrolase binding
GO:0046209 TAS nitric oxide metabolic process
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0051291 IEA protein heterooligomerization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000057454 Gchfr-001 protein_coding Mus_musculus 0 364

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