C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GTP cyclohydrolase I feedback regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000057454 Gchfr-001 ENSMUSG00000046814 10090 + 2:119167773-119172390 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057454
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057454 11.555±10.61 23.676±3.13 0.371±0.01 1.294±0.76 42.898±15.83 8.409±1.17 9.945±4.65 63.876±6.34 184.078±131.93 16.110±0.83 0.157±0.06 5.509±3.13 8.001±4.85 4.175±2.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070C CIL_00070C_0002 CGP 2:119137001-119172390
CIL_00070D CIL_00070D_0002 CGP 2:119167773-119208795

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004857 IEA enzyme inhibitor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006461 IEA protein complex assembly
GO:0009890 IEA negative regulation of biosynthetic process
GO:0016597 IEA amino acid binding
GO:0019899 IEA enzyme binding
GO:0030425 IEA dendrite
GO:0030742 IEA GTP-dependent protein binding
GO:0031965 IEA nuclear membrane
GO:0042470 IEA melanosome
GO:0043105 IEA negative regulation of GTP cyclohydrolase I activity
GO:0043234 IEA protein complex
GO:0044549 IEA GTP cyclohydrolase binding
GO:0051291 IEA protein heterooligomerization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000220496 DNAJC17-001 protein_coding Homo_sapiens 1.00053e-42 180
ENST00000260447 GCHFR-001 protein_coding Homo_sapiens 0 364
ENST00000558467 GCHFR-006 protein_coding Homo_sapiens 0 307
ENST00000558670 GCHFR-004 protein_coding Homo_sapiens 9.94922e-44 180
ENST00000559445 GCHFR-002 protein_coding Homo_sapiens 0 261
ENST00000559932 GCHFR-005 protein_coding Homo_sapiens 0 307

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