C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262493 GNAO1-001 ENSG00000087258 9606 + 16:56191390-56357444 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262493
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262493 0.119±0.00 0.451±0.00 0.056±0.00 40.950±13.60 0.058±0.00 4.390±0.00 0.793±0.60 0.742±0.51 0.273±0.00 0.159±0.00 0.156±0.00 0.197±0.09 0.150±0.00 7.025±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00048R CIL_00048R_0001 CGP 16:55846154-56357444
CIL_00048U CIL_00048U_0001 CGP 16:56191390-56425538

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA:IBA GTPase activity
GO:0004871 IEA:IBA signal transducer activity
GO:0005525 IEA GTP binding
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0006936 TAS muscle contraction
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IEA:IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007212 IBA dopamine receptor signaling pathway
GO:0019001 IEA guanyl nucleotide binding
GO:0031683 IEA:IBA G-protein beta/gamma-subunit complex binding
GO:0031821 IBA G-protein coupled serotonin receptor binding
GO:0031852 IBA mu-type opioid receptor binding
GO:0046872 IEA metal ion binding
GO:0051430 IBA corticotropin-releasing hormone receptor 1 binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034198 Gnao1-001 protein_coding Mus_musculus 0 2606
ENSMUST00000125716 Gnao1-002 protein_coding Mus_musculus 0 2252
ENSMUST00000138659 Gnao1-003 processed_transcript Mus_musculus 0 1290
ENSMUST00000125695 Gnao1-004 retained_intron Mus_musculus 0 1074
ENSDART00000149685 gnao1a-001 protein_coding Danio_rerio 0 952
ENSDART00000130125 gnao1a-201 protein_coding Danio_rerio 0 948
ENSMUST00000137202 Gnao1-006 protein_coding Mus_musculus 0 833
ENSMUST00000127900 Gnao1-007 nonsense_mediated_decay Mus_musculus 0 800
ENSMUST00000155245 Gnao1-010 retained_intron Mus_musculus 0 472
ENSMUST00000142466 Gnao1-011 protein_coding Mus_musculus 0 460
ENSMUST00000055704 Gnai2-201 protein_coding Mus_musculus 0 294
ENSMUST00000149530 Gnao1-005 protein_coding Mus_musculus 0 285
ENSMUST00000130974 Gnao1-008 retained_intron Mus_musculus 0 248
ENSMUST00000144451 Gnao1-009 processed_transcript Mus_musculus 4.00001e-41 174

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