C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262545 PCSK2-001 ENSG00000125851 9606 + 20:17226991-17484578 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastOvaryPlacentaTestisENST00000262545
Transcript ID Bladder Brain Breast Ovary Placenta Testis
ENST00000262545 0.021±0.00 5.512±4.06 0.018±0.00 0.552±0.02 0.116±0.00 0.679±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DI CIL_0002DI_0001 CGP 20:16748358-17484578
CIL_0007A3 CIL_0007A3_0002 CGP 20:17226107-17569220

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IEA endopeptidase activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0006508 IDA:IEA proteolysis
GO:0007399 IEA nervous system development
GO:0016020 IDA membrane
GO:0016485 IEA protein processing
GO:0016486 IEA peptide hormone processing
GO:0016540 IEA protein autoprocessing
GO:0030070 IDA insulin processing
GO:0030141 IEA secretory granule
GO:0030425 IEA dendrite
GO:0032403 IEA protein complex binding
GO:0034230 ISS enkephalin processing
GO:0034231 ISS islet amyloid polypeptide processing
GO:0034774 TAS secretory granule lumen
GO:0043025 IEA neuronal cell body
GO:0043204 IEA perikaryon
GO:0044267 TAS cellular protein metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028905 Pcsk2-002 protein_coding Mus_musculus 0 2641
ENSMUST00000124751 Pcsk2-001 processed_transcript Mus_musculus 0 475

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