C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proopiomelanocortin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264708 POMC-002 ENSG00000115138 9606 - 2:25160985-25168571 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverLungMuscleTestisENST00000264708
Transcript ID Liver Lung Muscle Testis
ENST00000264708 0.121±0.00 0.602±0.00 0.403±0.00 1.071±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000026 CIL_000026_0002 CGP 2:25042130-25168903

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001664 IDA G-protein coupled receptor binding
GO:0005102 IMP receptor binding
GO:0005179 ISS hormone activity
GO:0005576 IEA:TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005737 ISS cytoplasm
GO:0005782 IDA peroxisomal matrix
GO:0006091 IMP generation of precursor metabolites and energy
GO:0007165 IMP signal transduction
GO:0007218 IEA neuropeptide signaling pathway
GO:0007267 IMP cell-cell signaling
GO:0008217 ISS regulation of blood pressure
GO:0016486 TAS peptide hormone processing
GO:0030141 ISS secretory granule
GO:0031781 IPI type 3 melanocortin receptor binding
GO:0031782 IPI type 4 melanocortin receptor binding
GO:0032098 IMP regulation of appetite
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0033059 IMP cellular pigmentation
GO:0034774 TAS secretory granule lumen
GO:0044267 TAS cellular protein metabolic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070996 IDA type 1 melanocortin receptor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020990 Pomc-201 protein_coding Mus_musculus 0 226
ENSDART00000063333 pomca-001 protein_coding Danio_rerio 0.00000000000002 84

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