C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tet methylcytosine dioxygenase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265149 TET2-005 ENSG00000168769 9606 + 4:105146786-105279803 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000265149
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000265149 0.511±0.00 0.530±0.00 0.487±0.00 0.539±0.00 1.262±0.90 0.221±0.00 0.455±0.00 0.130±0.00 0.853±0.00 0.416±0.00 0.353±0.04 0.228±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00002E CIL_00002E_0002 CGP 4:104468312-105279816
CIL_0006P2 CIL_0006P2_0002 CGP 4:105145875-105474081

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0006211 IDA 5-methylcytosine catabolic process
GO:0006493 IDA protein O-linked glycosylation
GO:0007049 IEA cell cycle
GO:0008198 IDA ferrous iron binding
GO:0008270 IDA zinc ion binding
GO:0030099 IMP myeloid cell differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0055114 IEA oxidation-reduction process
GO:0070579 ISS methylcytosine dioxygenase activity
GO:0080111 IDA DNA demethylation
GO:0080182 IMP histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098603 Tet2-201 protein_coding Mus_musculus 0 1066
ENSDART00000090796 tet3-201 protein_coding Danio_rerio 2e-38 167
ENSDART00000137355 tet3-001 protein_coding Danio_rerio 2e-38 167

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