C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polymerase (DNA directed), alpha 2, accessory subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000265465 POLA2-001 ENSG00000014138 9606 + 11:65261762-65298685 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265465
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265465 0.611±0.00 1.976±0.00 0.272±0.00 1.406±0.00 1.144±0.00 0.903±0.31 0.383±0.28 1.081±0.80 0.300±0.03 1.360±0.00 0.139±0.00 2.612±0.38 1.858±0.79 2.462±0.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0001 VISTA 11:65187233-65790923

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0003674 ND molecular_function
GO:0003677 IEA DNA binding
GO:0003887 IEA DNA-directed DNA polymerase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005658 IBA alpha DNA polymerase:primase complex
GO:0005737 IDA cytoplasm
GO:0006260 NAS:IEA DNA replication
GO:0006270 IBA DNA replication initiation
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0046982 IBA protein heterodimerization activity
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025752 Pola2-201 protein_coding Mus_musculus 0 1520
ENSMUST00000165143 Pola2-202 protein_coding Mus_musculus 0 1437
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.00000003 66

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