C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pleckstrin homology domain interacting protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000275034 PHIP-001 ENSG00000146247 9606 - 6:78935867-79078236 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000275034
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000275034 3.898±0.00 1.709±0.00 3.558±0.00 4.349±0.75 6.321±3.90 5.521±1.01 2.184±0.57 2.555±0.83 4.660±4.06 7.199±2.39 1.779±0.61 3.859±2.23 4.536±3.78 6.572±3.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GD CIL_0006GD_0001 CGP 6:77690658-78946440
CIL_0006GA CIL_0006GA_0001 CGP 6:78867472-79078236
CIL_000621 CIL_000621_0002 CGP 6:78935867-79234738

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 ISS regulation of protein phosphorylation
GO:0005158 NAS insulin receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0006606 IEA protein import into nucleus
GO:0007010 IMP cytoskeleton organization
GO:0008284 ISS positive regulation of cell proliferation
GO:0008286 NAS insulin receptor signaling pathway
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0022604 IMP regulation of cell morphogenesis
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0040008 IEA regulation of growth
GO:0043066 ISS negative regulation of apoptotic process
GO:0043568 ISS positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045840 ISS positive regulation of mitosis
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070062 IDA extracellular vesicular exosome
GO:0070577 IDA lysine-acetylated histone binding
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034787 Phip-003 protein_coding Mus_musculus 0 9838
ENSMUST00000188868 Phip-010 retained_intron Mus_musculus 0 4274
ENSMUST00000190774 Phip-005 retained_intron Mus_musculus 0 4072
ENSMUST00000187021 Phip-004 retained_intron Mus_musculus 0 2957
ENSMUST00000189985 Phip-009 protein_coding Mus_musculus 0 1567
ENSMUST00000186089 Phip-012 nonsense_mediated_decay Mus_musculus 0 1491
ENSMUST00000188828 Phip-002 retained_intron Mus_musculus 0 1114
ENSMUST00000190838 Phip-018 retained_intron Mus_musculus 0 859
ENSMUST00000189927 Phip-014 retained_intron Mus_musculus 0 497
ENSMUST00000190822 Phip-016 nonsense_mediated_decay Mus_musculus 0 327
ENSMUST00000190405 Phip-007 retained_intron Mus_musculus 0 298
ENSMUST00000188850 Phip-011 retained_intron Mus_musculus 5e-40 172
ENSMUST00000189209 Phip-013 retained_intron Mus_musculus 2e-33 150
ENSMUST00000190101 Phip-006 retained_intron Mus_musculus 0.000000000000001 92

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