C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ankyrin 3, node of Ranvier (ankyrin G)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000280772 ANK3-001 ENSG00000151150 9606 - 10:60026298-60389730 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungOvaryTestisENST00000280772
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Ovary Testis
ENST00000280772 1.803±0.00 3.877±1.80 0.352±0.00 0.489±0.00 0.349±0.00 0.253±0.00 2.281±0.00 0.258±0.13 0.370±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002W5 CIL_0002W5_0002 CGP 10:59788763-60733490
CIL_0000GY CIL_0000GY_0002 CGP 10:60026298-60794852

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000281 IMP mitotic cytokinesis
GO:0005200 IMP structural constituent of cytoskeleton
GO:0005515 IPI:IEA protein binding
GO:0005764 IEA lysosome
GO:0005783 TAS endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0005923 IDA tight junction
GO:0007009 IMP plasma membrane organization
GO:0007016 TAS cytoskeletal anchoring at plasma membrane
GO:0007165 IEA signal transduction
GO:0007409 ISS axonogenesis
GO:0007411 IEA axon guidance
GO:0007528 IEA neuromuscular junction development
GO:0008092 ISS cytoskeletal protein binding
GO:0009925 IDA basal plasma membrane
GO:0009986 ISS cell surface
GO:0010628 ISS positive regulation of gene expression
GO:0010650 IEA positive regulation of cell communication by electrical coupling
GO:0010765 ISS positive regulation of sodium ion transport
GO:0014704 ISS intercalated disc
GO:0014731 ISS spectrin-associated cytoskeleton
GO:0016020 IEA membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0019228 ISS neuronal action potential
GO:0030018 IEA Z disc
GO:0030315 ISS T-tubule
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030507 ISS spectrin binding
GO:0030674 ISS protein binding, bridging
GO:0031594 IEA neuromuscular junction
GO:0033268 ISS node of Ranvier
GO:0033270 IEA paranode region of axon
GO:0034112 IEA positive regulation of homotypic cell-cell adhesion
GO:0042383 IDA sarcolemma
GO:0043001 IMP Golgi to plasma membrane protein transport
GO:0043005 IEA neuron projection
GO:0043034 TAS costamere
GO:0043194 ISS axon initial segment
GO:0043266 ISS regulation of potassium ion transport
GO:0044325 ISS ion channel binding
GO:0045184 IMP establishment of protein localization
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045296 ISS cadherin binding
GO:0045838 ISS positive regulation of membrane potential
GO:0050808 IEA synapse organization
GO:0071709 IMP membrane assembly
GO:0072659 IMP protein localization to plasma membrane
GO:0072660 IGI maintenance of protein location in plasma membrane
GO:0072661 IMP protein targeting to plasma membrane
GO:0090314 IEA positive regulation of protein targeting to membrane
GO:1900827 ISS positive regulation of membrane depolarization during cardiac muscle cell action potential
GO:2000651 ISS positive regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000182992 Ank3-005 protein_coding Mus_musculus 0 7369
ENSMUST00000186247 Ank3-038 protein_coding Mus_musculus 0 7073
ENSMUST00000092432 Ank3-204 protein_coding Mus_musculus 0 4806
ENSMUST00000092431 Ank3-203 protein_coding Mus_musculus 0 4680
ENSMUST00000182474 Ank3-003 retained_intron Mus_musculus 0 3539
ENSMUST00000092434 Ank3-205 protein_coding Mus_musculus 0 2961
ENSMUST00000182884 Ank3-001 protein_coding Mus_musculus 0 2961
ENSMUST00000054167 Ank3-202 protein_coding Mus_musculus 0 2889
ENSMUST00000183148 Ank3-015 protein_coding Mus_musculus 0 2889
ENSMUST00000183169 Ank3-014 protein_coding Mus_musculus 0 2889
ENSMUST00000182155 Ank3-011 protein_coding Mus_musculus 0 2889
ENSMUST00000182665 Ank3-029 nonsense_mediated_decay Mus_musculus 0 2050
ENSMUST00000182972 Ank3-016 protein_coding Mus_musculus 0 1864
ENSMUST00000181974 Ank3-024 protein_coding Mus_musculus 0 1857
ENSMUST00000182029 Ank3-022 protein_coding Mus_musculus 0 1857
ENSMUST00000092433 Ank3-018 protein_coding Mus_musculus 0 1857
ENSMUST00000182692 Ank3-030 protein_coding Mus_musculus 0 1857
ENSMUST00000182437 Ank3-026 protein_coding Mus_musculus 0 1808
ENSMUST00000183074 Ank3-021 protein_coding Mus_musculus 0 1808
ENSMUST00000183261 Ank3-020 protein_coding Mus_musculus 0 1808
ENSMUST00000182269 Ank3-019 protein_coding Mus_musculus 0 1808
ENSMUST00000182795 Ank3-025 protein_coding Mus_musculus 0 1759
ENSMUST00000047061 Ank3-201 protein_coding Mus_musculus 0 1580
ENSMUST00000182439 Ank3-027 protein_coding Mus_musculus 0 1580
ENSMUST00000182687 Ank3-023 retained_intron Mus_musculus 0 1502
ENSMUST00000183023 Ank3-006 protein_coding Mus_musculus 0 1133
ENSMUST00000182194 Ank3-013 retained_intron Mus_musculus 0 1026
ENSMUST00000182762 Ank3-028 retained_intron Mus_musculus 0 944
ENSMUST00000182373 Ank3-012 retained_intron Mus_musculus 0 922
ENSMUST00000182993 Ank3-009 protein_coding Mus_musculus 0 911
ENSMUST00000182162 Ank3-004 retained_intron Mus_musculus 0 909
ENSMUST00000183240 Ank3-032 protein_coding Mus_musculus 0 857
ENSMUST00000182557 Ank3-010 protein_coding Mus_musculus 0 821
ENSMUST00000183001 Ank3-036 retained_intron Mus_musculus 0 689
ENSMUST00000182683 Ank3-034 protein_coding Mus_musculus 0 678
ENSMUST00000185582 Ank3-039 protein_coding Mus_musculus 0 555
ENSMUST00000182606 Ank3-037 retained_intron Mus_musculus 0 514
ENSMUST00000182207 Ank3-031 protein_coding Mus_musculus 0 514
ENSMUST00000183075 Ank2-018 retained_intron Mus_musculus 0 479
ENSMUST00000182662 Ank2-026 protein_coding Mus_musculus 0 479
ENSMUST00000182764 Ank2-020 protein_coding Mus_musculus 0 479
ENSMUST00000182726 Ank2-027 protein_coding Mus_musculus 0 479
ENSMUST00000044443 Ank2-017 protein_coding Mus_musculus 0 479
ENSMUST00000182112 Ank2-028 protein_coding Mus_musculus 0 479
ENSMUST00000182704 Ank2-001 protein_coding Mus_musculus 0 479
ENSMUST00000182078 Ank2-022 protein_coding Mus_musculus 0 470
ENSMUST00000182594 Ank2-013 protein_coding Mus_musculus 0 411
ENSMUST00000182064 Ank2-008 protein_coding Mus_musculus 0 411
ENSMUST00000182779 Ank2-007 protein_coding Mus_musculus 0 411
ENSMUST00000182588 Ank2-014 protein_coding Mus_musculus 0 411
ENSMUST00000183082 Ank3-035 protein_coding Mus_musculus 0 411
ENSMUST00000182239 Ank3-033 retained_intron Mus_musculus 0 359
ENSDART00000088100 ank3b-201 protein_coding Danio_rerio 0 291
ENSMUST00000182142 Ank3-008 retained_intron Mus_musculus 0 244
ENSDART00000088106 ank3a-201 protein_coding Danio_rerio 5.99994e-41 176
ENSDART00000150037 ank3a-005 protein_coding Danio_rerio 5.99994e-41 176
ENSMUST00000182977 Ank2-021 protein_coding Mus_musculus 3e-34 154
ENSMUST00000182025 Ank2-032 nonsense_mediated_decay Mus_musculus 1e-22 115

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