C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: OTU deubiquitinase with linear linkage specificity
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000284274 OTULIN-001 ENSG00000154124 9606 + 5:14664748-14699711 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000284274
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000284274 1.632±0.00 0.622±0.00 1.757±0.00 1.080±0.09 1.106±0.64 1.127±0.62 1.449±0.14 2.246±0.20 1.941±0.12 3.036±0.70 0.986±0.42 3.208±1.65 2.142±0.64 2.428±0.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UF CIL_0007UF_0001 VISTA 5:14144246-14745917
CIL_0006MK CIL_0006MK_0003 CGP 5:14664664-14871778

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002040 ISS sprouting angiogenesis
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0008234 IMP cysteine-type peptidase activity
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0045087 IMP innate immune response
GO:0050728 IMP negative regulation of inflammatory response
GO:0060070 ISS canonical Wnt signaling pathway
GO:0070431 IMP nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0071797 IEA LUBAC complex
GO:1990108 IDA protein linear deubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000059662 Otulin-201 protein_coding Mus_musculus 0 1295

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