C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: CCR4-NOT transcription complex, subunit 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000285896 CNOT8-001 ENSG00000155508 9606 + 5:154858546-154876793 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000285896
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000285896 11.704±0.00 10.835±0.00 8.683±4.82 4.391±0.00 7.995±5.49 4.729±0.00 9.967±0.00 3.293±0.53 10.309±3.42 5.201±0.00 6.053±2.35 7.544±1.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088D CIL_00088D_0001 VISTA 5:154298500-154906275
CIL_00023V CIL_00023V_0001 CGP 5:154857553-154938209

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003676 IEA nucleic acid binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0004535 IDA poly(A)-specific ribonuclease activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IEA:NAS nucleus
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0030014 IDA CCR4-NOT complex
GO:0035195 TAS gene silencing by miRNA
GO:0043928 IDA exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0046872 IEA metal ion binding
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108843 Cnot8-003 protein_coding Mus_musculus 0 1088
ENSMUST00000020822 Cnot8-001 protein_coding Mus_musculus 0 1088
ENSMUST00000133923 Cnot8-004 processed_transcript Mus_musculus 0 239

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