C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: frizzled class receptor 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000286201 FZD7-001 ENSG00000155760 9606 + 2:202034587-202038445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000286201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000286201 3.957±0.00 6.043±0.00 0.970±0.00 1.069±0.58 8.320±5.59 10.977±9.19 2.967±2.10 4.139±4.09 4.731±4.47 1.920±0.92 3.692±1.26 11.509±8.95 6.255±0.89 5.435±2.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CR CIL_0009CR_0001 VISTA 2:201587932-202188948
CIL_0000JM CIL_0000JM_0002 CGP 2:201790461-202038445
CIL_00020N CIL_00020N_0001 CGP 2:202034587-202197862

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IBA Wnt signaling pathway, calcium modulating pathway
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0010812 IMP negative regulation of cell-substrate adhesion
GO:0014834 IEA skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
GO:0016020 IEA membrane
GO:0016021 TAS integral component of membrane
GO:0017147 IPI Wnt-protein binding
GO:0019827 IMP stem cell maintenance
GO:0030165 IPI PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0032589 IBA neuron projection membrane
GO:0033077 IEA T cell differentiation in thymus
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0035412 IMP regulation of catenin import into nucleus
GO:0035567 IEA non-canonical Wnt signaling pathway
GO:0038031 IMP non-canonical Wnt signaling pathway via JNK cascade
GO:0042327 IDA positive regulation of phosphorylation
GO:0042666 IMP negative regulation of ectodermal cell fate specification
GO:0042813 IBA Wnt-activated receptor activity
GO:0045177 IBA apical part of cell
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046330 IC positive regulation of JNK cascade
GO:0048103 IEA somatic stem cell division
GO:0060054 IMP positive regulation of epithelial cell proliferation involved in wound healing
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060231 IMP mesenchymal to epithelial transition
GO:0071300 ISS cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114246 Fzd7-001 protein_coding Mus_musculus 0 2606
ENSMUST00000057893 Fzd2-001 protein_coding Mus_musculus 0 928
ENSMUST00000054294 Fzd1-001 protein_coding Mus_musculus 0 745
ENSDART00000060789 fzd1-201 protein_coding Danio_rerio 0 673
ENSDART00000084055 fzd7a-001 protein_coding Danio_rerio 0 409
ENSDART00000076636 fzd2-001 protein_coding Danio_rerio 0 396
ENSMUST00000116133 Fzd5-002 protein_coding Mus_musculus 0 243
ENSMUST00000063982 Fzd5-001 protein_coding Mus_musculus 0 243
ENSMUST00000041080 Fzd8-201 protein_coding Mus_musculus 0 237
ENSDART00000112320 fzd4-201 protein_coding Danio_rerio 4e-22 111

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