C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: autocrine motility factor receptor, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290649 AMFR-001 ENSG00000159461 9606 - 16:56361452-56425538 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000290649
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000290649 6.544±0.00 4.328±0.00 3.024±0.00 8.286±3.78 7.997±6.17 7.754±1.55 7.551±4.76 20.421±9.63 19.449±0.00 7.249±5.40 46.055±41.41 7.461±4.54 7.510±1.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00048U CIL_00048U_0001 CGP 16:56191390-56425538
CIL_00048T CIL_00048T_0001 CGP 16:56361452-56452199

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000836 IDA Hrd1p ubiquitin ligase complex
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0004872 IPI receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006511 IMP ubiquitin-dependent protein catabolic process
GO:0006928 TAS cellular component movement
GO:0007165 TAS signal transduction
GO:0007568 IEA aging
GO:0007611 IEA learning or memory
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0016874 IEA ligase activity
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030425 IEA dendrite
GO:0030426 IEA growth cone
GO:0030433 IDA ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 IMP endoplasmic reticulum unfolded protein response
GO:0043025 IEA neuronal cell body
GO:0043234 IDA protein complex
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051259 IDA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053766 Amfr-001 protein_coding Mus_musculus 0 2813
ENSMUST00000139702 Amfr-003 retained_intron Mus_musculus 0 656
ENSMUST00000143265 Amfr-002 protein_coding Mus_musculus 0 411
ENSMUST00000137475 Amfr-004 processed_transcript Mus_musculus 0 327

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