C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: C-terminal binding protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290921 CTBP1-001 ENSG00000159692 9606 - 4:1211448-1249137 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290921
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290921 22.708±0.00 33.567±0.00 22.389±0.00 19.325±0.00 10.446±0.00 22.311±0.00 6.177±2.08 14.116±0.00 13.094±0.00 32.529±0.00 16.011±3.33 23.515±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LO CIL_0006LO_0001 CGP 4:1166932-1249953
CIL_0006LN CIL_0006LN_0001 CGP 4:1211448-1340147

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004616 IEA phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005667 IEA transcription factor complex
GO:0005829 IEA cytosol
GO:0006098 IEA pentose-phosphate shunt
GO:0006351 IEA transcription, DNA-templated
GO:0006468 TAS protein phosphorylation
GO:0007030 IEA Golgi organization
GO:0008022 TAS protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0008152 IEA metabolic process
GO:0008285 TAS negative regulation of cell proliferation
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 ISS transcriptional repressor complex
GO:0019079 TAS viral genome replication
GO:0019904 IPI protein domain specific binding
GO:0031065 IMP positive regulation of histone deacetylation
GO:0034401 IMP regulation of transcription by chromatin organization
GO:0035067 IMP negative regulation of histone acetylation
GO:0042803 IEA protein homodimerization activity
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0050872 ISS white fat cell differentiation
GO:0051287 ISS:IEA NAD binding
GO:0051726 IMP regulation of cell cycle
GO:0055114 IEA oxidation-reduction process
GO:0070491 IPI repressing transcription factor binding
GO:0090241 IMP negative regulation of histone H4 acetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000079746 Ctbp1-201 protein_coding Mus_musculus 0 2429
ENSDART00000059796 CTBP1-001 protein_coding Danio_rerio 0 900
ENSDART00000122739 ctbp1-201 protein_coding Danio_rerio 0 654
ENSDART00000079583 ctbp1-001 protein_coding Danio_rerio 0 654
ENSDART00000144367 ctbp1-002 protein_coding Danio_rerio 0 508
ENSDART00000121903 CABZ01109599.1-201 protein_coding Danio_rerio 0 361

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