C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000294066 MAP4K2-001 ENSG00000168067 9606 - 11:64789137-64803241 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000294066
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000294066 1.721±0.00 6.186±0.00 2.059±0.28 2.212±0.00 0.377±0.00 1.361±0.00 2.378±0.00 4.318±3.96 1.296±0.00 3.229±0.06 6.207±3.43 3.320±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005JE CIL_0005JE_0002 CGP 11:64788818-64811294

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006903 IEA vesicle targeting
GO:0006955 TAS immune response
GO:0007254 TAS JNK cascade
GO:0007257 IDA activation of JUN kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031435 IPI mitogen-activated protein kinase kinase kinase binding
GO:0035556 IDA intracellular signal transduction
GO:0045087 IEA innate immune response
GO:0046330 IDA positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025897 Map4k2-001 protein_coding Mus_musculus 0 2955
ENSMUST00000124556 Map4k2-002 nonsense_mediated_decay Mus_musculus 0 2758
ENSMUST00000142496 Map4k2-019 nonsense_mediated_decay Mus_musculus 0 2571
ENSMUST00000152259 Map4k2-004 retained_intron Mus_musculus 0 2170
ENSMUST00000133696 Map4k2-003 retained_intron Mus_musculus 0 1801
ENSMUST00000155569 Map4k2-008 processed_transcript Mus_musculus 0 850
ENSMUST00000137095 Map4k2-005 retained_intron Mus_musculus 0 822
ENSMUST00000130382 Map4k2-018 protein_coding Mus_musculus 0 758
ENSMUST00000123468 Map4k2-009 retained_intron Mus_musculus 0 632
ENSMUST00000154900 Map4k2-015 processed_transcript Mus_musculus 0 568
ENSMUST00000128170 Map4k2-022 nonsense_mediated_decay Mus_musculus 0 527
ENSMUST00000152349 Map4k2-007 nonsense_mediated_decay Mus_musculus 0 518
ENSMUST00000149624 Map4k2-010 processed_transcript Mus_musculus 0 503
ENSMUST00000127809 Map4k2-021 processed_transcript Mus_musculus 0 448
ENSMUST00000124333 Map4k2-020 retained_intron Mus_musculus 0 448
ENSMUST00000148410 Map4k2-011 retained_intron Mus_musculus 0 396
ENSMUST00000140098 Map4k2-016 retained_intron Mus_musculus 0 327
ENSMUST00000134307 Map4k2-012 retained_intron Mus_musculus 1e-25 122
ENSMUST00000126841 Map4k2-014 retained_intron Mus_musculus 5e-25 121

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