C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025897 Map4k2-001 ENSMUSG00000024948 10090 + 19:6341160-6355615 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryENSMUST00000025897
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENSMUST00000025897 11.562±2.09 21.380±0.32 16.907±2.19 14.243±4.38 37.001±13.23 11.788±1.20 9.768±2.78 11.516±4.08 7.394±2.78 54.443±11.00 3.838±0.89 22.220±5.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001YX CIL_0001YX_0002 CGP 19:6334979-6355615

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006468 ISS protein phosphorylation
GO:0006903 IDA vesicle targeting
GO:0007257 IEA activation of JUN kinase activity
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0035556 ISS intracellular signal transduction
GO:0045087 IEA innate immune response
GO:0046330 IEA positive regulation of JNK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000051236 mink1-202 protein_coding Danio_rerio 0.000007 58
ENSDART00000135260 mink1-001 protein_coding Danio_rerio 0.000007 58
ENST00000294066 MAP4K2-001 protein_coding Homo_sapiens 0 2955
ENST00000377350 MAP4K2-002 protein_coding Homo_sapiens 0 2878
ENST00000424945 MAP4K2-005 nonsense_mediated_decay Homo_sapiens 0 532
ENST00000433890 MAP4K2-014 nonsense_mediated_decay Homo_sapiens 0 2577
ENST00000435926 MAP4K2-012 nonsense_mediated_decay Homo_sapiens 0 2752
ENST00000439069 MAP4K2-006 protein_coding Homo_sapiens 0 758
ENST00000444560 MAP4K2-013 nonsense_mediated_decay Homo_sapiens 0 520
ENST00000468062 MAP4K2-010 processed_transcript Homo_sapiens 0 448
ENST00000470088 MAP4K2-004 retained_intron Homo_sapiens 0 614
ENST00000482314 MAP4K2-007 processed_transcript Homo_sapiens 0 448
ENST00000489952 MAP4K2-008 retained_intron Homo_sapiens 0 869
ENST00000493428 MAP4K2-011 retained_intron Homo_sapiens 0 623

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