C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: frizzled class receptor 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000295417 FZD5-001 ENSG00000163251 9606 - 2:207762586-207769563 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295417
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295417 2.195±0.00 1.061±0.00 1.117±0.00 0.671±0.27 2.869±0.75 7.472±2.45 0.545±0.09 5.157±1.21 3.770±3.01 3.630±0.36 0.524±0.01 4.039±3.47 3.189±1.80 0.558±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YT CIL_0006YT_0001 CGP 2:207711540-207769563
CIL_0006YS CIL_0006YS_0001 CGP 2:207762586-208025560

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000578 IDA embryonic axis specification
GO:0001525 IBA angiogenesis
GO:0001944 IEA vasculature development
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IBA cytoplasm
GO:0005769 IEA early endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IBA plasma membrane
GO:0005923 IEA tight junction
GO:0006915 IBA apoptotic process
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008285 IEA negative regulation of cell proliferation
GO:0008406 IBA gonad development
GO:0008595 IDA anterior/posterior axis specification, embryo
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016055 IEA Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0019901 IPI protein kinase binding
GO:0030165 IBA PDZ domain binding
GO:0030182 ISS neuron differentiation
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031076 IBA embryonic camera-type eye development
GO:0031077 IBA post-embryonic camera-type eye development
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032729 IMP positive regulation of interferon-gamma production
GO:0033077 IBA T cell differentiation in thymus
GO:0042813 IBA Wnt-activated receptor activity
GO:0042995 IBA cell projection
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0044332 IDA Wnt signaling pathway involved in dorsal/ventral axis specification
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IEA cell maturation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0060061 IDA Spemann organizer formation
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060561 IEA apoptotic process involved in morphogenesis
GO:0060670 IEA branching involved in labyrinthine layer morphogenesis
GO:0060715 IEA syncytiotrophoblast cell differentiation involved in labyrinthine layer development
GO:0060716 IBA labyrinthine layer blood vessel development
GO:0060718 IEA chorionic trophoblast cell differentiation
GO:0060828 IEA regulation of canonical Wnt signaling pathway
GO:0071219 IDA cellular response to molecule of bacterial origin
GO:1901382 IEA regulation of chorionic trophoblast cell proliferation
GO:2000810 IEA regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000063982 Fzd5-001 protein_coding Mus_musculus 0 2774
ENSMUST00000116133 Fzd5-002 protein_coding Mus_musculus 0 2593
ENSMUST00000041080 Fzd8-201 protein_coding Mus_musculus 0 305
ENSDART00000066835 fzd8a-001 protein_coding Danio_rerio 2.8026e-45 189
ENSDART00000112320 fzd4-201 protein_coding Danio_rerio 3e-20 106

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